PTGFR

Gene Symbol	PTGFR
Entrez Gene	5737
Alt Symbol	FP
Species	Human
Gene Type	protein-coding
Description	prostaglandin F receptor (FP)
Other Description	PGF receptor|PGF2 alpha receptor|PGF2-alpha receptor|prostaglandin F2 alpha receptor|prostaglandin F2-alpha receptor|prostaglandin receptor (2-alpha)|prostanoid FP receptor
Swissprots	P43088 Q2KHP3 Q9P1X4 Q6RYQ6 A8K9Y0
Accessions	BAA94756 BAE03222 CAI53641 CAI53647 EAX06350 EAX06351 P43088 AF004021 AAB63152 AK292845 BAF85534 AK312816 AY337000 AAQ76788 AY485530 AAR84381 BC112965 AAI12966 BG771316 BQ897935 CA429969 CD013876 DQ890957 ABM81883 DQ894120 ABM85046 H02113 L24470 AAA17684 XM_006710781 XP_006710844 XR_426624 XR_946715 NM_000959 NP_000950 NM_001039585 NP_001034674
Function	Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost. {ECO:0000250, ECO:0000269|PubMed:18587449}.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Eye. {ECO:0000269|PubMed:18587449}.
Top Pathways	Calcium signaling pathway, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Prostaglandin F2 alpha Receptor full length protein - ab159276 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human PTGFR Protein - H00005737-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

PTGFR - H00005737-G01 from Acris Antibodies Category Protein Prices $440.00 Sizes 2 µg Species Human

PTGFR - H00005737-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

PTGFR fusion protein - ag17065 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

PTGFR fusion protein - ag16173 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human PTGFR Protein - H00005737-G01 from Novus Biologicals Category Protein Prices $415.00 Sizes 2 µg Source Wheat Germ Species Human

Prostaglandin F2-alpha receptor (PTGFR), Recombinant Protein - MBS959937 from MyBioSource Category Protein Prices $1,375.00, $1,835.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PTGFR-Blocking-Peptide-Center - BP21723c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PTGFR Peptide, Human - M34GP12665H from Creative Peptides Category Peptide Source Synthetic. Species Human

Prostaglandin F2-alpha receptor (PTGFR), Recombinant Protein - MBS7028219 from MyBioSource Category Protein Prices $1,170.00, $2,155.00, $3,360.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Search more