PTGFR

Gene Symbol PTGFR
Entrez Gene 5737
Alt Symbol FP
Species Human
Gene Type protein-coding
Description prostaglandin F receptor (FP)
Other Description PGF receptor|PGF2 alpha receptor|PGF2-alpha receptor|prostaglandin F2 alpha receptor|prostaglandin F2-alpha receptor|prostaglandin receptor (2-alpha)|prostanoid FP receptor
Swissprots P43088 Q2KHP3 Q9P1X4 Q6RYQ6 A8K9Y0
Accessions BAA94756 BAE03222 CAI53641 CAI53647 EAX06350 EAX06351 P43088 AF004021 AAB63152 AK292845 BAF85534 AK312816 AY337000 AAQ76788 AY485530 AAR84381 BC112965 AAI12966 BG771316 BQ897935 CA429969 CD013876 DQ890957 ABM81883 DQ894120 ABM85046 H02113 L24470 AAA17684 XM_006710781 XP_006710844 XR_426624 XR_946715 NM_000959 NP_000950 NM_001039585 NP_001034674
Function Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost. {ECO:0000250, ECO:0000269|PubMed:18587449}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Eye. {ECO:0000269|PubMed:18587449}.
Top Pathways Calcium signaling pathway, Neuroactive ligand-receptor interaction

PGF2αR CRISPR/Cas9 KO Plasmid (h) - sc-402974 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGF2αR HDR Plasmid (h) - sc-402974-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGF2αR Double Nickase Plasmid (h) - sc-402974-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGF2αR Double Nickase Plasmid (h2) - sc-402974-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGF2αR CRISPR Activation Plasmid (h) - sc-402974-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGF2αR CRISPR Activation Plasmid (h2) - sc-402974-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGF2αR Lentiviral Activation Particles (h) - sc-402974-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGF2αR Lentiviral Activation Particles (h2) - sc-402974-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PGF2αR siRNA (h) - sc-44987 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PGF2αR shRNA Plasmid (h) - sc-44987-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PGF2αR shRNA (h) Lentiviral Particles - sc-44987-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PTGFR RNAi - H00005737-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU042111 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17671 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17671 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PTGFR siRNA (Human) - CRH3879 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PTGFR (NM_000959.3) - SHH386064 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PTGFR(NM_000959.3) - SHR106788 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PTGFR(NM_001039585.1) - SHR106816 from Creative biogene

Category siRNA
Species Reactivities Human

PTGFR shRNA Plasmid (Human) - CHH3879 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PTGFR miRNA 3'UTR clone - MiUTR1H-08424 from Creative biogene

Species Reactivities Human

PTGFR miRNA 3'UTR clone - MiUTR1H-08425 from Creative biogene

Species Reactivities Human
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