Gene Symbol | AXIN2 |
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Entrez Gene | 8313 |
Alt Symbol | AXIL, ODCRCS |
Species | Human |
Gene Type | protein-coding |
Description | axin 2 |
Other Description | axin-2|axin-like protein|axis inhibition protein 2|conductin |
Swissprots | Q9UH84 Q9H3M6 Q3MJ88 Q9Y2T1 |
Accessions | EAW89003 EAW89004 EAW89005 EAW89006 Q9Y2T1 AB052751 BAB19762 AF078165 AAD20976 AF205888 AAF22799 AK025718 AK315303 BC006295 AAH06295 BC101533 AAI01534 BC143244 AAI43245 BE670767 CB306601 CR933657 CAI45956 CX756263 CX759580 DA785881 DA839648 XM_011525319 XP_011523621 XM_011525320 XP_011523622 XM_011525321 XP_011523623 XM_011525322 XP_011523624 NM_004655 NP_004646 |
Function | Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta- catenin and APC by GSK3B (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Expressed in brain and lymphoblast. |
Top Pathways | Wnt signaling pathway, Basal cell carcinoma, Colorectal cancer, Endometrial cancer, Hippo signaling pathway |
Human Axin 2 full length protein - ab132310 from Abcam
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Human Axin 2 protein fragment - ab92262 from Abcam
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Mouse Axin 2 peptide - ab32195 from Abcam
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Mouse Axin 2 peptide - ab32196 from Abcam
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AXIN2 / Axin 2 Antibody Blocking Peptide - LS-E31067 from LifeSpan Bioscience
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Recombinant Human Axin-2 Protein - H00008313-Q02 from Novus Biologicals
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Recombinant Human Axin-2 Protein - H00008313-P01 from Novus Biologicals
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Recombinant Human Axin-2 Protein - H00008313-Q01 from Novus Biologicals
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Axin-2 Blocking Peptide - NBP1-76526PEP from Novus Biologicals
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Human AXIN2 Protein - abx065489 from Abbexa
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Axin-2 - H00008313-P01 from Acris Antibodies
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Axin-2 - H00008313-P01-10 from Acris Antibodies
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Axin-2 - H00008313-Q01-10 from Acris Antibodies
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Axin-2 - H00008313-Q01-25 from Acris Antibodies
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Axin-2 - H00008313-Q02 from Acris Antibodies
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Axin-2 - H00008313-Q02-10 from Acris Antibodies
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Axin-2 - H00008313-Q02-25 from Acris Antibodies
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Axin-2 control peptide - AP26091CP-N from Acris Antibodies
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Axis Inhibition Protein 2 (AXIN2), Human - 20-8409 from ARP American Research Products
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AXIN2 Peptide - 6163P from ProSci
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AXIN2 fusion protein - Ag14574 from Proteintech Group
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AXIN2 Peptide - 350495 from ABBIOTEC
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Recombinant Human AXIN2, GST-tagged - AXIN2-10085H from Creative Biomart
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Recombinant Human AXIN2, His-tagged - AXIN2-3796H from Creative Biomart
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Recombinant Axis Inhibition Protein 2 (AXIN2) - RPC192Hu01 from Uscn Life Science Inc.
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