AXIN2

Gene Symbol AXIN2
Entrez Gene 8313
Alt Symbol AXIL, ODCRCS
Species Human
Gene Type protein-coding
Description axin 2
Other Description axin-2|axin-like protein|axis inhibition protein 2|conductin
Swissprots Q9UH84 Q9H3M6 Q3MJ88 Q9Y2T1
Accessions EAW89003 EAW89004 EAW89005 EAW89006 Q9Y2T1 AB052751 BAB19762 AF078165 AAD20976 AF205888 AAF22799 AK025718 AK315303 BC006295 AAH06295 BC101533 AAI01534 BC143244 AAI43245 BE670767 CB306601 CR933657 CAI45956 CX756263 CX759580 DA785881 DA839648 XM_011525319 XP_011523621 XM_011525320 XP_011523622 XM_011525321 XP_011523623 XM_011525322 XP_011523624 NM_004655 NP_004646
Function Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta- catenin and APC by GSK3B (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm.
Tissue Specificity Expressed in brain and lymphoblast.
Top Pathways Wnt signaling pathway, Basal cell carcinoma, Colorectal cancer, Endometrial cancer, Hippo signaling pathway

Axin2 (D48G4) Rabbit mAb - 5863 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D48G4
Western blot analysis of extracts from HCT-15 and SW620 cells using Axin2 (D48G4) Rabbit mAb.

Axin2 (76G6) Rabbit mAb - 2151 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone 76G6
Western blot analysis of total cell lysates from HCT15 and SW620 cells, using Axin2 (76G2) Rabbit mAb.

Conductin (H-260) - sc-20784 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Conductin (H-260): sc-20784. Western blot analysis of Conductin expression in DU 145 nuclear extract.

Conductin (C-6) - sc-25302 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Conductin (C-6): sc-25302. Western blot analysis of Conductin expression in SW480 whole cell lysate.

Conductin (M-20) - sc-8570 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Conductin (M-20): sc-8570. Western blot analysis of Conductin expression in Jurkat whole cell lysate.

Anti-Axin 2 antibody - ab32197 from Abcam

Prices $391.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab32197 staining Axin2 in mouse colon sections. Secondary antibody conjugated to Alexa-fluor ® 488 (please see Abreview for further details)See Abreview

Anti-Axin 2 antibody - ab107613 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Axin 2 antibody (ab107613) at 1 µg/ml + Mouse lung tissue lysate at 15 µg

Anti-Axin 2 antibody - ab185821 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence analysis of U2OS cells using ab185821. Blue DAPI for nuclear staining.

Anti-Axin 2 antibody - ab133223 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed, paraffin embedded Human uterus tissue labelling Axin 2 with ab133223 at 5 ug/ml, followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Axin 2 antibody [EPR2005(2)] - ab109307 from Abcam

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2005(2)
All lanes : Anti-Axin 2 antibody [EPR2005(2)] (ab109307) at 1/1000 dilution (unpurified)Lane 1 : SW480 cell lysateLane 2 : C6 cell lysateLane 3 : PC-12 cell lysateLane 4 : NIH/3T3 cell lysateLysates/proteins at 20 µg per lane.SecondaryPeroxidase-conjugated goat anti-rabbit IgG (H+L) at 1/1000 dilution

Anti-Axin 2 antibody - C-terminal - ab168826 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Axin 2 antibody - C-terminal (ab168826) at 1/100 dilution + Jurkat cell line lysates at 35 µg

Anti-AXIN2 / Axin 2 Antibody - LS-C332132 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human lung cancer using AXIN2 antibody at dilution of 1:200 (x400 lens).

Anti-AXIN2 / Axin 2 Antibody (aa28-309) IHC-plus™ - LS-B11618 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-AXIN2 / Axin 2 Antibody (C-Terminus) IHC-plus™ - LS-B7029 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-AXIN2 / AXIL antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7029 concentration 5 ug/ml.

Anti-AXIN2 / Axin 2 Antibody (Pro556) - LS-C35080 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal

Anti-AXIN2 / Axin 2 Antibody (aa823-853, APC) - LS-C252170 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AXIN2 / Axin 2 Antibody (aa823-853, AP) - LS-C252169 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AXIN2 / Axin 2 Antibody (aa823-853, Biotin) - LS-C252171 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AXIN2 / Axin 2 Antibody (aa823-853, FITC) - LS-C252172 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AXIN2 / Axin 2 Antibody (aa823-853, Azide-free, HRP) - LS-C252173 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AXIN2 / Axin 2 Antibody (aa350-631, Biotin) - LS-C298157 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AXIN2 / Axin 2 Antibody (aa350-631, FITC) - LS-C302679 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AXIN2 / Axin 2 Antibody (aa823-853, PE) - LS-C252174 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AXIN2 / Axin 2 Antibody (aa823-853) - LS-C329248 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AXIN2 / Axin 2 Antibody (clone 3B6) - LS-C198546 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3B6
Detection limit for recombinant GST tagged AXIN2 is 0.3 ng/ml as a capture antibody.
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