KIF14

Gene Symbol	KIF14
Entrez Gene	9928
Alt Symbol	MKS12
Species	Human
Gene Type	protein-coding
Description	kinesin family member 14
Other Description	kinesin-like protein KIF14
Swissprots	Q15058 Q14CI8 Q5T1W3 Q4G0A5
Accessions	CAI40582 CBX51368 EAW91315 EAW91316 EAW91317 Q15058 BC098582 AAH98582 BC113742 AAI13743 BC144068 BE644769 BQ425495 CN307042 CR748178 D26361 BAA05392 HQ258545 ADR83299 XM_011510230 XP_011508532 XM_011510231 XP_011508533 XM_011510232 XP_011508534 XM_011510233 XP_011508535 XM_011510234 XP_011508536 XM_011510235 XP_011508537 XM_011510236 XP_011508538 NM_001305792 NP_001292721 NM_014875 NP_055690
Function	Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed:24784001, PubMed:16648480). During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively (PubMed:16431929). Regulates cell growth through regulation of cell cycle progression and cytokinesis (PubMed:24854087). During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, resulting in positive regulation of cyclins, including CCNE1, CCND1 and CCNB1 (PubMed:24854087). During late neurogenesis, regulates the cerebellar, cerebral cortex and olfactory bulb development through regulation of apoptosis, cell proliferation and cell division (By similarity). Also is required for chromosome congres
Subcellular Location	Nucleus {ECO:0000269|PubMed:16431929}. Cytoplasm {ECO:0000269|PubMed:16648480}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:16431929}. Midbody {ECO:0000269|PubMed:16431929, ECO:0000269|PubMed:20309963}. Note=Nuclear localization observed during interphase (PubMed:16431929). Nuclear localization triggered by entry into mitosis (PubMed:16648480). Cytoplasmic in interphase (PubMed:16648480). Cytoplasmic in metaphase cells (PubMed:16431929). From prophase to metaphase, accumulates at the developing spindle poles and their associated microtubules. During anaphase, accumulates at the spindle midzone. Localization to the central spindle and midbody during anaphase is dependent upon PRC1 and CIT presence. In cells ready to undergo abscission, concentrates at the contractile ring. {ECO:0000269|PubMed:16431929, ECO:0000269|PubMed:16648480}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

KIF14 (E-3) - sc-365553 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

KIF14 (C-18) - sc-48560 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

KIF14 (H-240) - sc-134591 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

KIF14 (C-14) - sc-48559 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

KIF14 (K-15) - sc-48561 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

KIF14 (K-20) - sc-48562 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-KIF14 antibody - ab71155 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KIF14 antibody - ab3747 from Abcam Prices $370.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-KIF14 antibody - ab3746 from Abcam Prices $370.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-KIF14 antibody - ab92429 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KIF14 Antibody - LS-C71359 from LifeSpan Bioscience Prices $575.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KIF14 Antibody - LS-C71360 from LifeSpan Bioscience Prices $575.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KIF14 Antibody (C-Terminus) - LS-C71361 from LifeSpan Bioscience Prices $545.00 Sizes 20 µg Host Rabbit Clonality Polyclonal

Anti-KIF14 Antibody (aa50-100) - LS-C287145 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KIF14 Antibody (N-Terminus) - LS-C155210 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KIF14 Antibody (C-Terminus) - LS-C287750 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KIF14 Antibody (aa900-950) - LS-C287149 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KIF14 Antibody (C-Terminus) - LS-C286691 from LifeSpan Bioscience Prices $415.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

KIF14 Antibody - NB100-254 from Novus Biologicals Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

KIF14 Antibody - H00009928-B01 from Novus Biologicals Prices $349.00 Sizes 50 µl Host Mouse Clonality Polyclonal

KIF14 Antibody - NB100-243 from Novus Biologicals Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

KIF14 Antibody - NB110-40678 from Novus Biologicals Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

KIF14 Antibody - NBP1-83055 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

KIF14 Antibody - NBP2-17047 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Kif14 protein Polyclonal Antibody - bs-2494R from Bioss Prices $269.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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