CHTF18

Gene Symbol CHTF18
Entrez Gene 63922
Alt Symbol C16orf41, C321D2.2, C321D2.3, C321D2.4, CHL12, Ctf18, RUVBL
Species Human
Gene Type protein-coding
Description CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
Other Description C321D2.3 (novel protein)|C321D2.4 (novel protein)|chromosome transmission fidelity protein 18 homolog|hCTF18|homolog of yeast CHL12|some homology with holliday junction DNA helicase RUVB like
Swissprots B7ZBA2 Q9BRG5 Q9BR83 Q9H7K3 Q7Z6Y6 Q7Z6Y4 Q8WVB6 D3DU68
Accessions AAK61256 EAW85704 EAW85705 EAW85706 EAW85707 EAW85708 EAW85709 EAW85710 EAW85711 Q8WVB6 AI650845 AK024476 BAB15766 AK128869 AK293846 BAG57244 AK309804 BC006278 AAH06278 BC006437 AAH06437 BC018184 AAH18184 DC410609 XM_005255470 XP_005255527 XM_005255471 XP_005255528 XM_005255472 XP_005255529 XM_011522572 XP_011520874 XM_011522573 XP_011520875 NM_022092 NP_071375
Function Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single- stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (PCNA). The CTF18- RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH. {ECO:0000269|PubMed:12766176, ECO:0000269|PubMed:12930902, ECO:0000269|PubMed:17545166}.
Subcellular Location Nucleus {ECO:0000269|PubMed:12766176}. Note=Associates with chromatin during S phase.

CHTF18 HEK293 Cell Transient Overexpression Lysate (Non-Denatured) - L035T6 from Acris Antibodies

Category Cell Lysate
Prices $290.00
Sizes 100 µg

CHTF18 overexpression lysate - LY411774 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

CHTF18 Overexpression Lysate (Native) - NBP2-06469 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: CHTF18 Overexpression Lysate (Adult Normal) [NBP2-06469] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CHTF18.

Panoply™ Human CHTF18 Knockdown Stable Cell Line - CSC-DC003161 from Creative biogene

Category Cell Line
Species Human
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