CHTF18

Gene Symbol	CHTF18
Entrez Gene	63922
Alt Symbol	C16orf41, C321D2.2, C321D2.3, C321D2.4, CHL12, Ctf18, RUVBL
Species	Human
Gene Type	protein-coding
Description	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
Other Description	C321D2.3 (novel protein)|C321D2.4 (novel protein)|chromosome transmission fidelity protein 18 homolog|hCTF18|homolog of yeast CHL12|some homology with holliday junction DNA helicase RUVB like
Swissprots	B7ZBA2 Q9BRG5 Q9BR83 Q9H7K3 Q7Z6Y6 Q7Z6Y4 Q8WVB6 D3DU68
Accessions	AAK61256 EAW85704 EAW85705 EAW85706 EAW85707 EAW85708 EAW85709 EAW85710 EAW85711 Q8WVB6 AI650845 AK024476 BAB15766 AK128869 AK293846 BAG57244 AK309804 BC006278 AAH06278 BC006437 AAH06437 BC018184 AAH18184 DC410609 XM_005255470 XP_005255527 XM_005255471 XP_005255528 XM_005255472 XP_005255529 XM_011522572 XP_011520874 XM_011522573 XP_011520875 NM_022092 NP_071375
Function	Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single- stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (PCNA). The CTF18- RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH. {ECO:0000269|PubMed:12766176, ECO:0000269|PubMed:12930902, ECO:0000269|PubMed:17545166}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:12766176}. Note=Associates with chromatin during S phase.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CHTF18 protein fragment - ab163755 from Abcam Category Protein Source Wheat germ Species Human

CHTF18 / RUVBL Antibody Blocking Peptide - LS-E2094 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CHTF18 / RUVBL Antibody Blocking Peptide - LS-E21026 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CHTF18 / RUVBL Antibody Blocking Peptide - LS-E21025 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CHTF18 Partial Recombinant Protein - H00063922-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CHTF18-Antibody-C-term-Blocking-peptide - BP12986b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CHTF18 Blocking Peptide - 33R-7466 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CHTF18 Blocking Peptide - 33R-8631 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CHTF18 - H00063922-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CHTF18 - H00063922-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CHTF18 fusion protein - ag3672 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Chromosome transmission fidelity protein 18 homolog(CHTF18) ,p - CSB-YP848822HU CSB-EP848822HU CSB-BP848822HU CSB-MP848822HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CHTF18 Peptide, Human - M34GP03161H from Creative Peptides Category Peptide Source Synthetic. Species Human

CHTF18 Recombinant Protein Antigen - NBP2-58935PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

Chromosome transmission fidelity protein 18 homolog (CHTF18), partial, Recombinant Protein - MBS1392517 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

CHTF18 Recombinant Protein Antigen - NBP2-55371PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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