HOOK1

Gene Symbol HOOK1
Entrez Gene 51361
Alt Symbol HK1
Species Human
Gene Type protein-coding
Description hook microtubule-tethering protein 1
Other Description h-hook1|hHK1|hook homolog 1|protein Hook homolog 1
Swissprots A8MU44 Q5TG44 O60561 B4DX15 Q9UJC3 A8K8E9
Accessions EAX06615 EAX06616 Q9UJC3 AA576610 AF044923 AAC09298 AK027250 AK097735 AK098561 AK292314 BAF85003 AK301768 BAG63227 BC011621 AAH11621 BC107857 AAI07858 DQ891957 ABM82883 DQ895143 ABM86069 XM_006710676 XP_006710739 XM_011541562 XP_011539864 XM_011541563 XP_011539865 XR_246271 XR_946665 NM_015888 NP_056972
Function Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). {ECO:0000250}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:11238449}. Note=Localizes to the spermatid manchette during spermiogenesis but is not present in mature spermatozoa (By similarity). Localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, the Golgi complex, multivesicular bodies (MVBs), lysosomes, or mitochondria. Often found in close association with microtubules. {ECO:0000250}.

HOOK1 (C-20) - sc-49972 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HOOK1 (C-20): sc-49972. Western blot analysis of HOOK1 expression in human tonsil (A), rat pancreas (B) and mouse testis (C) tissue extracts and SJRH30 (D), WiDR (E) and U-251-MG (F) whole cell lysates.

HOOK1 (E-6) - sc-398233 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HOOK1 (E-6): sc-398233. Western blot analysis of HOOK1 expression in MCF7 (A), Caco-2 (B) and HEK293T (C) whole cell lysates and human testis tissue extract (D).

HOOK1 (H-46) - sc-366030 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

HOOK1 (S-20) - sc-49975 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

HOOK1 (JA.25) - sc-130453 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
HOOK1 (JA.25): sc-130453. Western blot analysis of HOOK1 expression in MCF7 whole cell lysate.

Anti-HOOK1 antibody - ab103533 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-HOOK1 antibody (ab103533) at 1/500 dilution + Human pancreas tissue lysate at 50 µg

Anti-HOOK1 antibody - ab68769 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-HOOK1 antibody (ab68769) at 1/500 dilutionLane 1 : HOOK1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L) at 1/2500 dilution

Anti-HOOK1 antibody [EPR10102] - ab151756 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10102
All lanes : Anti-HOOK1 antibody [EPR10102] (ab151756) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : MCF-7 cell lysateLane 3 : Caco-2 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-HOOK1 antibody [EPR10103(B)] - ab150397 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10103(B)
All lanes : Anti-HOOK1 antibody [EPR10103(B)] (ab150397) at 1/1000 dilutionLane 1 : A673 cell lysateLane 2 : MCF7 cell lysateLane 3 : 293T cell lysateLysates/proteins at 10 µg per lane.

Anti-HOOK1 Antibody (aa632-729, clone 10D195, Azide-free) - LS-C183688 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 10D195

Anti-HOOK1 Antibody (aa402-431, PE) - LS-C258728 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HOOK1 Antibody (aa402-431, AP) - LS-C259818 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HOOK1 Antibody (aa402-431, Azide-free, HRP) - LS-C258727 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HOOK1 Antibody (aa402-431, APC) - LS-C259819 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HOOK1 Antibody (aa402-431, Biotin) - LS-C259820 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HOOK1 Antibody (aa402-431, FITC) - LS-C259821 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HOOK1 Antibody - LS-C310642 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HOOK1 Antibody (aa464-513) - LS-C145357 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HOOK1 antibody LS-C145357 Western blot of Fetal Heart lysate. Antibody concentration 1 ug/ml.

Anti-HOOK1 Antibody (aa400-431) - LS-C322031 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HOOK1 Antibody (aa402-431) - LS-C159860 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HOOK1 Antibody western blot of WiDr cell line lysates (35 ug/lane). The HOOK1 antibody detected the HOOK1 protein (arrow).

Anti-HOOK1 Antibody (clone 1D11) - LS-C134067 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D11
Immunoperoxidase of monoclonal antibody to HOOK1 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]

HOOK1 Antibody - H00051361-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: HOOK1 Antibody [H00051361-D01P] - Analysis of HOOK1 expression in mouse testis.

HOOK1 Antibody - NBP1-81745 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: HOOK1 Antibody [NBP1-81745] - Staining of human testis shows moderate cytoplasmic positivity in spermatids.

HOOK1 Antibody - NBP1-81744 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HOOK1 Antibody [NBP1-81744] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

HOOK1 Antibody (1D11) - H00051361-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D11
Western Blot: HOOK1 Antibody (1D11) [H00051361-M02] - OK1 monoclonal antibody (M02), clone 1D11. Western Blot analysis of HOOK1 expression in MCF-7 ( Cat # L046V1 ).
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