HOOK1

Gene Symbol	HOOK1
Entrez Gene	51361
Alt Symbol	HK1
Species	Human
Gene Type	protein-coding
Description	hook microtubule-tethering protein 1
Other Description	h-hook1|hHK1|hook homolog 1|protein Hook homolog 1
Swissprots	A8MU44 Q5TG44 O60561 B4DX15 Q9UJC3 A8K8E9
Accessions	EAX06615 EAX06616 Q9UJC3 AA576610 AF044923 AAC09298 AK027250 AK097735 AK098561 AK292314 BAF85003 AK301768 BAG63227 BC011621 AAH11621 BC107857 AAI07858 DQ891957 ABM82883 DQ895143 ABM86069 XM_006710676 XP_006710739 XM_011541562 XP_011539864 XM_011541563 XP_011539865 XR_246271 XR_946665 NM_015888 NP_056972
Function	Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). {ECO:0000250}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:11238449}. Note=Localizes to the spermatid manchette during spermiogenesis but is not present in mature spermatozoa (By similarity). Localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, the Golgi complex, multivesicular bodies (MVBs), lysosomes, or mitochondria. Often found in close association with microtubules. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HOOK1 protein (His-DHFR tag) - ab127454 from Abcam Category Protein Prices $364.00 Sizes 50 µg Source E. coli Species Human

Human HOOK1 full length protein - ab132778 from Abcam Category Protein Source Wheat germ Species Human

HOOK1 Antibody Blocking Peptide - LS-E2208 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HOOK1 Antibody Blocking Peptide - LS-E22673 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human HOOK1 Protein - H00051361-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

HOOK1 Recombinant Protein - H00051361-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

HOOK1-Antibody-Center-Blocking-Peptide - BP13130c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HOOK1 - H00051361-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

HOOK1 - H00051361-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

HOOK1 - H00051361-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

HOOK1 - H00051361-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

HOOK1 fusion protein - ag1311 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Protein Hook homolog 1(HOOK1) - CSB-YP891526HU CSB-EP891526HU CSB-BP891526HU CSB-MP891526HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

HOOK1 - TP302517 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

HOOK1 Recombinant Protein Antigen - NBP1-81745PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

HOOK1 Recombinant Protein Antigen - NBP1-81744PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

HOOK1 Peptide, Human - M34GP07176H from Creative Peptides Category Peptide Source Synthetic. Species Human

Protein Hook homolog 1 (HOOK1), Recombinant Protein - MBS1468914 from MyBioSource Category Protein Prices $1,540.00, $1,540.00, $1,765.00, $1,765.00, $2,640.00, $2,640.00, $3,085.00, $3,085.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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