NOP10

Gene Symbol	NOP10
Entrez Gene	55505
Alt Symbol	DKCB1, NOLA3, NOP10P
Species	Human
Gene Type	protein-coding
Description	NOP10 ribonucleoprotein
Other Description	H/ACA ribonucleoprotein complex subunit 3|NOP10 ribonucleoprotein homolog|homolog of yeast Nop10p|nucleolar protein 10|nucleolar protein family A member 3|nucleolar protein family A, member 3 (H/ACA small nucleolar RNPs)|snoRNP protein NOP10
Swissprots	Q9NPE3
Accessions	BAA96107 CBG17030 CBV30476 EAW92303 Q9NPE3 AB043104 BAA96133 BC008886 AAH08886 BC063023 AAH63023 BM554889 BQ218536 NM_018648 NP_061118
Function	Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. {ECO:0000269|PubMed:15044956}.
Subcellular Location	Nucleus, nucleolus {ECO:0000269|PubMed:11074001}. Nucleus, Cajal body {ECO:0000269|PubMed:11074001}. Note=Also localized to Cajal bodies (coiled bodies).
Top Pathways	Ribosome biogenesis in eukaryotes

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NOP10 protein fragment - ab153400 from Abcam Category Protein Source Wheat germ Species Human

NOP10 Antibody Blocking Peptide - LS-E20901 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NOP10 Protein - H00055505-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NOLA3 Blocking Peptide - 33R-5997 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NOLA3 - H00055505-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NOLA3 - H00055505-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NOP10 fusion protein - Ag18978 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

NOP10 fusion protein - ag18718 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human NOP10 - NOP10-794H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human H/ACA ribonucleoprotein complex subunit 3(NOP10) - CSB-YP873610HU CSB-EP873610HU CSB-BP873610HU CSB-MP873610HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NOLA3 (full length, N-term HIS tag) - TP760624 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

NOP10 Protein - NBP2-32441PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

NOP10 Peptide, Human - M34GP10501H from Creative Peptides Category Peptide Source Synthetic. Species Human

H/ACA ribonucleoprotein complex subunit 3 (NOP10), Recombinant Protein - MBS1306926 from MyBioSource Category Protein Prices $785.00, $785.00, $1,010.00, $1,010.00, $1,095.00, $1,095.00, $1,550.00, $1,550.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Debaryomyces

H/ACA ribonucleoprotein complex subunit 3 (NOP10), Recombinant Protein - MBS1328967 from MyBioSource Category Protein Prices $785.00, $785.00, $1,010.00, $1,010.00, $1,090.00, $1,090.00, $1,550.00, $1,550.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Kluyveromyces

H/ACA ribonucleoprotein complex subunit 3 (NOP10), Recombinant Protein - MBS1356907 from MyBioSource Category Protein Prices $785.00, $785.00, $1,010.00, $1,010.00, $1,090.00, $1,090.00, $1,550.00, $1,550.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Ashbya gossypii

H/ACA ribonucleoprotein complex subunit 3 (NOP10), Recombinant Protein - MBS1281983 from MyBioSource Category Protein Prices $790.00, $790.00, $1,015.00, $1,015.00, $1,105.00, $1,105.00, $1,565.00, $1,565.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

H/ACA ribonucleoprotein complex subunit 3 (NOP10), Recombinant Protein - MBS1329603 from MyBioSource Category Protein Prices $785.00, $785.00, $1,010.00, $1,010.00, $1,090.00, $1,090.00, $1,550.00, $1,550.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 100 µg (Baculovirus), 1 mg (E-Coli), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Candida

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