NOP10

Gene Symbol NOP10
Entrez Gene 55505
Alt Symbol DKCB1, NOLA3, NOP10P
Species Human
Gene Type protein-coding
Description NOP10 ribonucleoprotein
Other Description H/ACA ribonucleoprotein complex subunit 3|NOP10 ribonucleoprotein homolog|homolog of yeast Nop10p|nucleolar protein 10|nucleolar protein family A member 3|nucleolar protein family A, member 3 (H/ACA small nucleolar RNPs)|snoRNP protein NOP10
Swissprots Q9NPE3
Accessions BAA96107 CBG17030 CBV30476 EAW92303 Q9NPE3 AB043104 BAA96133 BC008886 AAH08886 BC063023 AAH63023 BM554889 BQ218536 NM_018648 NP_061118
Function Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. {ECO:0000269|PubMed:15044956}.
Subcellular Location Nucleus, nucleolus {ECO:0000269|PubMed:11074001}. Nucleus, Cajal body {ECO:0000269|PubMed:11074001}. Note=Also localized to Cajal bodies (coiled bodies).
Top Pathways Ribosome biogenesis in eukaryotes

Nop10 CRISPR/Cas9 KO Plasmid (h) - sc-417292 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nop10 HDR Plasmid (h) - sc-417292-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nop10 Double Nickase Plasmid (h) - sc-417292-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nop10 Double Nickase Plasmid (h2) - sc-417292-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nop10 CRISPR Activation Plasmid (h) - sc-417292-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nop10 CRISPR Activation Plasmid (h2) - sc-417292-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nop10 Lentiviral Activation Particles (h) - sc-417292-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nop10 Lentiviral Activation Particles (h2) - sc-417292-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nop10 siRNA (h) - sc-90082 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nop10 shRNA Plasmid (h) - sc-90082-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nop10 shRNA (h) Lentiviral Particles - sc-90082-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU104671 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15411 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15411 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01776 from Sigma-Aldrich

Category miRNA

NOP10 siRNA (Human) - CRJ0714 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NOP10 (NM_018648.3) - SHH353660 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human NOLA3(NM_018648.3) - SHR016094 from Creative biogene

Category siRNA
Species Reactivities Human

Human NOP10 siRNA - orb271215 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NOP10 shRNA Plasmid (Human) - CHJ0714 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NOP10 miRNA 3'UTR clone - MiUTR1H-06842 from Creative biogene

Species Reactivities Human
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