CYP17A1

Gene Symbol CYP17A1
Entrez Gene 1586
Alt Symbol CPT7, CYP17, P450C17, S17AH
Species Human
Gene Type protein-coding
Description cytochrome P450, family 17, subfamily A, polypeptide 1
Other Description 17-alpha-hydroxyprogesterone aldolase|CYPXVII|cytochrome P450 17A1|cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia|cytochrome P450-C17|cytochrome P450c17|cytochrome p450 XVIIA1|steroid 17-alpha-hydroxylase/17,20 lyase|steroid 17-alpha-monooxygenase
Swissprots Q5TZV7 P05093
Accessions AAA36405 AAA52140 AAA59984 ABF50972 ABF93457 ABY87534 ACT99720 EAW49672 P05093 AI492406 AK094106 AK289898 BAF82587 AK308466 AK312235 BAG35168 BC032843 BC062997 AAH62997 BC063388 AAH63388 BT020000 AAV38803 DA013587 DA016804 M14564 AAA52151 NM_000102 NP_000093
Function Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty. {ECO:0000269|PubMed:22266943}.
Subcellular Location Membrane {ECO:0000305}.
Top Pathways Steroid hormone biosynthesis, Prolactin signaling pathway, Ovarian steroidogenesis

CYP17A1 (D-12) - sc-374244 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP17A1 (D-12): sc-374244. Western blot analysis of CYP17A1 expression in non-transfected: sc-117752 (A) and human CYP17A1 transfected: sc-116774 (B) 293T whole cell lysates.

CYP17A1 (H-48) - sc-66849 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CYP17A1 (H-48): sc-66849. Western blot analysis of CYP17A1 expression in non-transfected: sc-117752 (A) and human CYP17A1 transfected: sc-116774 (B) 293T whole cell lysates.

CYP17A1 (M-80) - sc-66850 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CYP17A1 (M-80): sc-66850. Western blot analysis of CYP17A1 expression HeLa nuclear extract.

CYP17A1 (N-17) - sc-46084 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP17A1 (N-17): sc-46084. Western blot analysis of CYP17A1 expression in SW-13 (A) and ES-2 (B) whole cell lysates.

CYP17A1 (N-18) - sc-46085 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CYP17A1 (G-4) - sc-376711 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP17A1 (G-4): sc-376711. Western blot analysis of CYP17A1 expression in non-transfected: sc-117752 (A) and human CYP17A1 transfected: sc-116774 (B) 293T whole cell lysates.

CYP17A1 (C-12) - sc-46080 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Cytochrome P450 17A1 antibody - ab80206 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Cytochrome P450 17A1 antibody (ab80206) at 1/50 dilution + K562 cell line lysates at 35 µg

Anti-Cytochrome P450 17A1 antibody - ab64886 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cytochrome P450 17A1 antibody (ab64886) at 1/500 dilutionLane 1 : extracts from A549 cells (5-30µg total protein)Lane 2 : extracts from Jurkat cells (5-30µg total protein)Lane 3 : extracts from HeLa cells (5-30µg total protein)Lane 4 : extracts from HeLa cells (5-30µg total protein) and 5-10µg of the immunising peptide.

Anti-Cytochrome P450 17A1 antibody - ab125876 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Cytochrome P450 17A1 antibody (ab125876) at 1/10000 dilution + MCF-7 cell lysate at 30 µg

Anti-Cytochrome P450 17A1 antibody [5G10] - ab118988 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5G10
All lanes : Anti-Cytochrome P450 17A1 antibody [5G10] (ab118988) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY Cytochrome P450 17A1 cDNALysates/proteins at 5 µg per lane.

Anti-Cytochrome P450 17A1 antibody [EPR6293] - ab125022 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6293
All lanes : Anti-Cytochrome P450 17A1 antibody [EPR6293] (ab125022) at 1/1000 dilutionLane 1 : Human adrenal gland lysateLane 2 : SK-OV-3 lysateLane 3 : HeLa lysateLane 4 : Jurkat lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Cytochrome P450 17A1 antibody [EPR6294(2)] - ab134910 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6294(2)
Anti-Cytochrome P450 17A1 antibody [EPR6294(2)] (ab134910) at 1/10000 dilution + Human adrenal gland lysate at 10 µgSecondaryHRP-conjugated goat anti-rabbit IgG polyclonal at 1/2000 dilution

Anti-Cytochrome P450 17A1 antibody - C-terminal - ab197951 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling Cytochrome P450 17A1 with ab197951 at 1/30 dilution.

Anti-CYP17 / CYP17A1 Antibody - LS-C317774 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP17 / CYP17A1 Antibody (FITC) - LS-C317773 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP17 / CYP17A1 Antibody - LS-C155201 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: MCF-7 7.5% SDS PAGE CYP17A1 antibody diluted at 1:10000

Anti-CYP17 / CYP17A1 Antibody (Asn249) - LS-C176850 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
IHC of CYP17A1 (N249) pAb in paraffin-embedded human breast carcinoma tissue.

Anti-CYP17 / CYP17A1 Antibody (C-Terminus, clone EPR6294(2)) - LS-C154671 from LifeSpan Bioscience

Host Rabbit
Clonality Monoclonal
Clone EPR6294(2)
IHC of paraffin-embedded human testis tissue using anti-CYP17A1 antibody.

Anti-CYP17 / CYP17A1 Antibody (Internal, clone EPR6293) IHC-plus™ - LS-B6749 from LifeSpan Bioscience

Host Rabbit
Clonality Monoclonal
Clone [EPR6293]
Anti-CYP17A1 antibody IHC of human testis, Leydig cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6749 dilution 1:50.

Anti-CYP17 / CYP17A1 Antibody - LS-C342021 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CYP17 / CYP17A1 Antibody - LS-C334511 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of HeLa cell line, using CYP17A1 antibody.

Anti-CYP17 / CYP17A1 Antibody - LS-C331434 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using CYP17A1 antibody.

Anti-CYP17 / CYP17A1 Antibody (clone 5G10) - LS-C337466 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 5G10
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP17A1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP17A1.

Anti-CYP17 / CYP17A1 Antibody (Internal) IHC-plus™ - LS-B8295 from LifeSpan Bioscience

Host Goat
Clonality Polyclonal
Anti-CYP17 / CYP17A1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8295 dilution 3.75 ug/ml.
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