Gene Symbol | CYP17A1 |
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Entrez Gene | 1586 |
Alt Symbol | CPT7, CYP17, P450C17, S17AH |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome P450, family 17, subfamily A, polypeptide 1 |
Other Description | 17-alpha-hydroxyprogesterone aldolase|CYPXVII|cytochrome P450 17A1|cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia|cytochrome P450-C17|cytochrome P450c17|cytochrome p450 XVIIA1|steroid 17-alpha-hydroxylase/17,20 lyase|steroid 17-alpha-monooxygenase |
Swissprots | Q5TZV7 P05093 |
Accessions | AAA36405 AAA52140 AAA59984 ABF50972 ABF93457 ABY87534 ACT99720 EAW49672 P05093 AI492406 AK094106 AK289898 BAF82587 AK308466 AK312235 BAG35168 BC032843 BC062997 AAH62997 BC063388 AAH63388 BT020000 AAV38803 DA013587 DA016804 M14564 AAA52151 NM_000102 NP_000093 |
Function | Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty. {ECO:0000269|PubMed:22266943}. |
Subcellular Location | Membrane {ECO:0000305}. |
Top Pathways | Steroid hormone biosynthesis, Prolactin signaling pathway, Ovarian steroidogenesis |
Human Cytochrome P450 17A1 full length protein - ab152320 from Abcam
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Human Cytochrome P450 17A1 peptide - ab48065 from Abcam
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CPT1A Antibody Blocking Peptide - LS-E6987 from LifeSpan Bioscience
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CYP17 / CYP17A1 Antibody Blocking Peptide - LS-E26083 from LifeSpan Bioscience
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CYP17 / CYP17A1 Antibody Blocking Peptide - LS-E9340 from LifeSpan Bioscience
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Recombinant Human Cytochrome P450 17A1 Protein - H00001586-P01 from Novus Biologicals
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CYP17A1-Antibody-Center-Blocking-Peptide - BP7879c from Abgent, a WuXi AppTec company
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Human CYP17A1 protein - orb246322 from Biorbyt
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CYP17A1 peptide - orb217189 from Biorbyt
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Cytochrome P450 17A1 Blocking Peptide - abx062520 from Abbexa
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Cytochrome P450 17A1 Peptide - AC21-0911-P from Abcore
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CYP17A1 - H00001586-P01 from Acris Antibodies
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CYP17A1 Peptide - 45-446P from ProSci
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CYP17A1 fusion protein - ag5899 from Proteintech Group
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CYP17A1 fusion protein - Ag5998 from Proteintech Group
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Recombinant Human CYP17A1, GST-tagged - CYP17A1-11763H from Creative Biomart
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Recombinant Human CYP17A1 - CYP17A1-928H from Creative Biomart
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Recombinant Human Cytochrome P450 17A1 - CYP17A1-01H from Creative Biomart
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Cytochrome P450 17A1 Blocking Peptide - CBP1326 from Cohesion Biosciences
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CYP17A1 (N249) Peptide - BS2187P from Bioworld Technology
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Recombinant human Steroid 17-alpha-hydroxylase/17,20 lyase - CSB-YP006392HU(H) CSB-BP006392HU(H) CSB-MP006392HU(H) from Cusabio
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Recombinant Human Steroid 17-alpha-hydroxylase/17,20 lyase - CSB-YP006392HU(G) CSB-BP006392HU(G) CSB-MP006392HU(G) from Cusabio
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Recombinant human Steroid 17-alpha-hydroxylase/17,20 lyase - CSB-EP006392HU(H) from Cusabio
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Recombinant Human Steroid 17-alpha-hydroxylase/17,20 lyase - CSB-EP006392HU(G) from Cusabio
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Recombinant Human Steroid 17-alpha-hydroxylase/17,20 lyase(CYP17A1) - CSB-YP006392HU CSB-BP006392HU CSB-MP006392HU from Cusabio
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