Gene Symbol | DPT |
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Entrez Gene | 1805 |
Alt Symbol | TRAMP |
Species | Human |
Gene Type | protein-coding |
Description | dermatopontin |
Other Description | tyrosine-rich acidic matrix protein |
Swissprots | A8K981 Q07507 Q9UIX8 Q8N4R2 |
Accessions | EAW90830 Q07507 AF086330 AI699890 AL049455 BC033736 AAH33736 BP257325 DQ892055 ABM82981 DQ895249 ABM86175 Z22865 CAA80487 NM_001937 NP_001928 |
Function | Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
Tissue Specificity | Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts. {ECO:0000269|PubMed:10233760, ECO:0000269|PubMed:8104875}. |
Human Dermatopontin full length protein - ab158310 from Abcam
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Human Dermatopontin full length protein - ab182823 from Abcam
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Human Dermatopontin protein fragment - ab158311 from Abcam
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Dermatopontin / DPT Antibody Blocking Peptide - LS-E1830 from LifeSpan Bioscience
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Dermatopontin / DPT Antibody Blocking Peptide - LS-E9000 from LifeSpan Bioscience
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Dermatopontin / DPT Antibody Blocking Peptide - LS-E15461 from LifeSpan Bioscience
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Dermatopontin Recombinant Protein - H00001805-P01 from Novus Biologicals
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Dermatopontin Partial Recombinant Protein - H00001805-Q01 from Novus Biologicals
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DPT-Antibody-N-term-Blocking-peptide - BP12641a from Abgent, a WuXi AppTec company
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DPT-Antibody-Center-Blocking-Peptide - BP7485c from Abgent, a WuXi AppTec company
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Recombinant Human Dermatopontin, CF - 4629-DP-050 from R&D Systems
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DPT Protein Lysate (APL10339) - APL10339 from Aviva Systems Biology
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Human Dermatopontin Protein - abx066306 from Abbexa
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Dermatopontin - H00001805-P01-10 from Acris Antibodies
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Dermatopontin - H00001805-P01-25 from Acris Antibodies
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Dermatopontin - H00001805-Q01-10 from Acris Antibodies
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Dermatopontin - H00001805-Q01-25 from Acris Antibodies
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Dermatopontin (DPT), Human - 20-8480 from ARP American Research Products
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DPT fusion protein - ag0801 from Proteintech Group
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DPT fusion protein - Ag6200 from Proteintech Group
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Recombinant Human DPT, His-tagged - DPT-322H from Creative Biomart
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Recombinant Dermatopontin (DPT) - RPC432Hu01 from Uscn Life Science Inc.
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Recombinant Dermatopontin (DPT) - RPC432Mu01 from Uscn Life Science Inc.
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Recombinant Dermatopontin (DPT) - RPC432Mu02 from Uscn Life Science Inc.
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Recombinant Human Dermatopontin Protein, CF - 4629-DP from R&D Systems
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