DPT

Gene Symbol	DPT
Entrez Gene	1805
Alt Symbol	TRAMP
Species	Human
Gene Type	protein-coding
Description	dermatopontin
Other Description	tyrosine-rich acidic matrix protein
Swissprots	A8K981 Q07507 Q9UIX8 Q8N4R2
Accessions	EAW90830 Q07507 AF086330 AI699890 AL049455 BC033736 AAH33736 BP257325 DQ892055 ABM82981 DQ895249 ABM86175 Z22865 CAA80487 NM_001937 NP_001928
Function	Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation (By similarity). {ECO:0000250}.
Subcellular Location	Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Tissue Specificity	Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts. {ECO:0000269\|PubMed:10233760, ECO:0000269\|PubMed:8104875}.

Dermatopontin (F-4) - sc-376863 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

Dermatopontin (F-4): sc-376863. Western blot analysis of Dermatopontin expression in non-transfected: sc-117752 (A) and human Dermatopontin transfected: sc-115088 (B) 293T whole cell lysates.

Dermatopontin (FL-201) - sc-366333 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Dermatopontin (S-14) - sc-160280 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Dermatopontin (S-14): sc-160280. Western blot analysis of Dermatopontin expression in non-transfected: sc-117752 (A) and human Dermatopontin transfected: sc-115088 (B) 293T whole cell lysates.

Anti-Dermatopontin antibody - ab85162 from Abcam

Prices	$370.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Dermatopontin antibody (ab85162) at 1/50 dilution + HL60 cell line lysates at 35 µg

Anti-Dermatopontin antibody - ab112600 from Abcam

Prices	$370.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-Dermatopontin antibody (ab112600) at 1/50 dilutionLane 1 : 293 cell line lysatesLane 2 : 293 cell line lysates, transiently transfected with the Dermatopontin geneLysates/proteins at 2 µg per lane.

Anti-Dermatopontin antibody - ab118710 from Abcam

Prices	$359.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Dermatopontin antibody (ab118710) at 1 µg/ml + Mouse pancreas lysate at 10 µgSecondaryGoat anti-Rabbit IgG-HRP

Anti-Dermatopontin / DPT Antibody (aa19-201) - LS-C184218 from LifeSpan Bioscience

Prices	$605.00
Sizes	100 µg
Host	Sheep
Clonality	Polyclonal

Anti-Dermatopontin / DPT Antibody (aa45-94) - LS-C145639 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

DPT / Dermatopontin antibody LS-C145639 Western blot of Mouse Pancreas lysate. Antibody concentration 1 ug/ml.

Anti-Dermatopontin / DPT Antibody (aa26-197, Biotin) - LS-C298399 from LifeSpan Bioscience

Prices	$435.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Dermatopontin / DPT Antibody (aa29-197, Biotin) - LS-C298400 from LifeSpan Bioscience

Prices	$435.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Dermatopontin / DPT Antibody (aa26-197, FITC) - LS-C305091 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Dermatopontin / DPT Antibody (aa29-197, FITC) - LS-C305092 from LifeSpan Bioscience

Prices	$465.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Dermatopontin / DPT Antibody (aa26-197) - LS-C293672 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of recombinant Dermatopontin / DPT.

Anti-Dermatopontin / DPT Antibody (clone 2A11) - LS-C197075 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2A11

Detection limit for recombinant GST tagged DPT is 0.1 ng/ml as a capture antibody.

Anti-Dermatopontin / DPT Antibody (aa29-197) - LS-C293673 from LifeSpan Bioscience

Prices	$415.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Dermatopontin / DPT Antibody (aa45-72) - LS-C167524 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

DPT Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human pancreas tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-Dermatopontin / DPT Antibody (aa102-128) - LS-C100698 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Formalin-fixed and paraffin-embedded human brain with DPT Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Dermatopontin Antibody - NBP2-14930 from Novus Biologicals

Prices	$349.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: Dermatopontin Antibody [NBP2-14930] - A: Non-transfected lysate. B: DPT transfected lysate. 12% SDS PAGE, antibody diluted at 1:500.

Dermatopontin Antibody - NB110-68135 from Novus Biologicals

Prices	$399.00
Sizes	150 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: Dermatopontin Antibody [NB110-68135] - Mouse skin tissue were subjected to SDS PAGE followed by western blot at dilution of 1:1000

Dermatopontin Antibody - AF4629 from Novus Biologicals

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Sheep
Clonality	Polyclonal

Western blot shows lysates of human heart tissue. PVDF Membrane was probed with 1 µg/mL of Human Dermatopontin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4629) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for Dermatopontin at approximately 22 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

Dermatopontin Antibody (2A11) - H00001805-M08 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2A11

Sandwich ELISA: Dermatopontin Antibody (2A11) [H00001805-M08] - Detection limit for recombinant GST tagged DPT is 0.1 ng/ml as a capture antibody.

Monoclonal Anti-DPT, (C-terminal) antibody produced in mouse - SAB1402755 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2A11

<B>ELISA</B><BR/>Monoclonal Anti-DPT: <B>Cat. No. SAB1402755</B>: Detection limit for recombinant GST tagged DPT is 0.1 ng/mL.

Anti-DPT (161-175) antibody produced in rabbit - D8945 from Sigma-Aldrich

Prices	$328.50
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunofluorescence</B><BR/>Anti-DPT (161-175), <B>Cat. No. D8945</B>: Immunofluorescence of HUVEC cells using Anti-DPT (161-175), D8945 (red), taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-DPT (26-40) antibody produced in rabbit - D8820 from Sigma-Aldrich

Prices	$328.50
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunofluorescence</B><BR/>Anti-DPT (26-40): <B>Cat. No. D8820</B>: Immunofluorescence of HUVEC cells using DPT (26-40), Cat. No. D8820 (red) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

DPT-Antibody-N-term - AP12641a from Abgent, a WuXi AppTec company

Prices	$99.00, $295.00
Sizes	80 µl, 400 µl
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of DPT (arrow) using rabbit polyclonal DPT Antibody (N-term) (Cat. #AP12641a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DPT gene.

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