STXBP1

Gene Symbol	STXBP1
Entrez Gene	6812
Alt Symbol	MUNC18-1, NSEC1, P67, RBSEC1, UNC18
Species	Human
Gene Type	protein-coding
Description	syntaxin binding protein 1
Other Description	N-Sec1|neuronal SEC1|protein unc-18 homolog 1|protein unc-18 homolog A|syntaxin-binding protein 1|unc-18A|unc18-1
Swissprots	Q96TG8 Q28208 P61764 Q64320 Q62759 B1AM97
Accessions	EAW87679 EAW87681 P61764 AB209180 BAD92417 AF004562 AAC39688 AF004563 AAC39689 AK094794 AK293984 BAH11641 AK295154 BAH11993 AK295802 BAH12190 BC015749 AAH15749 D63851 BAA19483 DC325017 DQ895426 ABM86352 EU176334 ABW03785 Y12723 CAA73255 NM_001032221 NP_001027392 NM_003165 NP_003156
Function	May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
Subcellular Location	Cytoplasm. Membrane; Peripheral membrane protein.
Tissue Specificity	Brain and spinal cord. Highly enriched in axons.
Top Pathways	Synaptic vesicle cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Munc18-1 protein fragment - ab114603 from Abcam Category Protein Source Wheat germ Species Human

Munc18-1 peptide - ab4982 from Abcam Category Peptide

STXBP1 / MUNC18-1 Antibody Blocking Peptide - LS-E10722 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

STXBP1 / MUNC18-1 Antibody Blocking Peptide - LS-E25620 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Syntaxin-BP1 Protein - H00006812-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Syntaxin-BP1 Protein - H00006812-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Munc18-1 blocking peptide - GTX89288-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse

Human STXBP1 His GST tag protein - orb84097 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source Insect Species Human

STXBP1 Blocking Peptide - 33R-9269 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Munc 18-1 Peptide - AC21-0451-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

STXBP1 / UNC18A - H00006812-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

STXBP1 / UNC18A - H00006812-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

STXBP1 / UNC18A - H00006812-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

STXBP1 / UNC18A - H00006812-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

STXBP1 / UNC18A control peptide - SP5259CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

MUNC18 Peptide - 45-916P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse

STXBP1 fusion protein - Ag1978 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human STXBP1, His & GST tagged - STXBP1-3924H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human STXBP1 - STXBP1-28545TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human STXBP1, GST-tagged - STXBP1-3034H from Creative Biomart Category Protein Source E.coli Species Human

Human STXBP1 / UNC18A Protein (His & GST Tag) - 11751-H20B-100 from Sino Biological Category Protein Prices $348.00, $348.00 Sizes 20 µg, 100 µg Source Baculovirus-Insect Cells Species Human

Recombinant Human Syntaxin-binding protein 1(STXBP1) - CSB-YP022905HU CSB-EP022905HU CSB-BP022905HU CSB-MP022905HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

STXBP1 / UNC18A (transcript variant 2) - TP304873 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

STXBP1 / UNC18A (transcript variant 1) - TP318471 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

MUNC18/STXBP1, Peptide - MBS425992 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse

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