STXBP1

Gene Symbol STXBP1
Entrez Gene 6812
Alt Symbol MUNC18-1, NSEC1, P67, RBSEC1, UNC18
Species Human
Gene Type protein-coding
Description syntaxin binding protein 1
Other Description N-Sec1|neuronal SEC1|protein unc-18 homolog 1|protein unc-18 homolog A|syntaxin-binding protein 1|unc-18A|unc18-1
Swissprots Q96TG8 Q28208 P61764 Q64320 Q62759 B1AM97
Accessions EAW87679 EAW87681 P61764 AB209180 BAD92417 AF004562 AAC39688 AF004563 AAC39689 AK094794 AK293984 BAH11641 AK295154 BAH11993 AK295802 BAH12190 BC015749 AAH15749 D63851 BAA19483 DC325017 DQ895426 ABM86352 EU176334 ABW03785 Y12723 CAA73255 NM_001032221 NP_001027392 NM_003165 NP_003156
Function May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
Subcellular Location Cytoplasm. Membrane; Peripheral membrane protein.
Tissue Specificity Brain and spinal cord. Highly enriched in axons.
Top Pathways Synaptic vesicle cycle

Unc18-1 CRISPR/Cas9 KO Plasmid (h) - sc-403761 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Unc18-1 HDR Plasmid (h) - sc-403761-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Unc18-1 Double Nickase Plasmid (h) - sc-403761-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Unc18-1 Double Nickase Plasmid (h2) - sc-403761-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Unc18-1 CRISPR Activation Plasmid (h) - sc-403761-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Unc18-1 CRISPR Activation Plasmid (h2) - sc-403761-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Unc18-1 Lentiviral Activation Particles (h) - sc-403761-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Unc18-1 Lentiviral Activation Particles (h2) - sc-403761-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Unc18-1 siRNA (h) - sc-42308 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Unc18-1 shRNA Plasmid (h) - sc-42308-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Unc18-1 shRNA (h) Lentiviral Particles - sc-42308-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Syntaxin-BP1 RNAi - H00006812-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Syntaxin-BP1 RNAi - H00006812-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU093941 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20791 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20791 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

STXBP1 siRNA (Human) - CRH4657 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

STXBP1 - MBS8226247 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human STXBP1 (NM_003165.3) - SHH420432 from Creative biogene

Category siRNA
Species Reactivities Human

Human STXBP1 siRNA - orb265159 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

STXBP1 shRNA Plasmid (Human) - CHH4657 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

STXBP1 miRNA 3'UTR clone - MiUTR3H-05418 from Creative biogene

Species Reactivities Human

STXBP1 miRNA 3'UTR clone - MiUTR3H-05419 from Creative biogene

Species Reactivities Human
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