C9orf142

Gene Symbol C9orf142
Entrez Gene 286257
Alt Symbol PAXX
Species Human
Gene Type protein-coding
Description chromosome 9 open reading frame 142
Other Description paralog of XRCC4 and XLF|protein PAXX
Swissprots Q9BUH6 Q8IY19
Accessions EAW88324 EAW88325 EAW88326 EAW88327 EAW88328 Q9BUH6 BC002613 AAH02613 BC038191 AAH38191 HQ447605 ADQ32091 NM_183241 NP_899064
Function Involved in DNA non-homologous end joining (NHEJ). May act as a scaffold required to stabilize the Ku heterodimer, composed of XRCC5/Ku80 and XRCC6/Ku70, at DNA ends and thus promote assembly and/or stability of the NHEJ machinery at double- strand break (DSB) sites. {ECO:0000269|PubMed:25574025}.
Subcellular Location Nucleus {ECO:0000269|PubMed:25574025}. Note=Predominantly localizes to the nucleus. Accumulates at sites of DNA damage generated by laser microirradiation. {ECO:0000269|PubMed:25574025}.

C9orf142-Over-expression-Lysate - LY15845a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag C9orf142 (arrow) using his tag antibody. 293T cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the C9orf142 gene‘

C9orf142 overexpression lysate - LY405236 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

C9orf142 Overexpression Lysate (Native) - NBP2-04782 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: C9orf142 Overexpression Lysate (Adult Normal) [NBP2-04782] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for C9orf142.

Panoply™ Human C9ORF142 Knockdown Stable Cell Line - CSC-DC002192 from Creative biogene

Category Cell Line
Species Human
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