Gene Symbol | H1FNT |
---|---|
Entrez Gene | 341567 |
Alt Symbol | H1.7, H1T2 |
Species | Human |
Gene Type | protein-coding |
Description | H1 histone family, member N, testis-specific |
Other Description | HANP1|haploid germ cell-specific nuclear protein 1|histone H1t2|testis-specific H1 histone |
Swissprots | Q147U8 Q75WM6 Q7Z694 Q5GKZ5 |
Accessions | AAS49492 Q75WM6 AB121028 BAD13382 AY302593 AAP60022 BC118635 AAI18636 BC119787 AAI19788 NM_181788 NP_861453 |
Function | Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone- protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1 (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Note=In round and elongating spermatids, specifically localizes to a chromatin domain at the apical pole. {ECO:0000250}. |
Tissue Specificity | Testis-specific. {ECO:0000269|PubMed:16533358}. |
H1FNT fusion protein - ag18140 from Proteintech Group
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H1FNT fusion protein - ag18159 from Proteintech Group
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Recombinant Human Testis-specific H1 histone(H1FNT) - CSB-YP762309HU CSB-EP762309HU CSB-BP762309HU CSB-MP762309HU from Cusabio
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Testis-specific H1 histone (H1FNT), Recombinant Protein - MBS1450651 from MyBioSource
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Histone H1t2 Recombinant Protein Antigen - NBP2-30774PEP from Novus Biologicals
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H1FNT-Blocking-Peptide-N-Term - BP21787a from Abgent, a WuXi AppTec company
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H1FNT Peptide, Human - M34GP06800H from Creative Peptides
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