TNFSF15

Gene Symbol TNFSF15
Entrez Gene 9966
Alt Symbol TL1, TL1A, VEGI, VEGI192A
Species Human
Gene Type protein-coding
Description tumor necrosis factor (ligand) superfamily, member 15
Other Description TNF ligand-related molecule 1|TNF superfamily ligand TL1A|tumor necrosis factor ligand superfamily member 15|vascular endothelial cell growth inhibitor|vascular endothelial growth inhibitor-192A
Swissprots Q5VWH1 Q8NFE9 O95150 Q3SX69 Q5VJK8
Accessions BAJ13472 BAJ13473 CAV13212 EAW87431 O95150 AF039390 AAD08783 AF520785 AAM77366 AK291642 BAF84331 AK313721 AW014795 AY434464 AAR98573 BC069435 AAH69435 BC074940 AAH74940 BC074941 AAH74941 BC104462 AAI04463 BC104463 AAI04464 NM_001204344 NP_001191273 NM_005118 NP_005109
Function Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. {ECO:0000269|PubMed:10597252, ECO:0000269|PubMed:11911831, ECO:0000269|PubMed:11923219, ECO:0000269|PubMed:9872942}.
Subcellular Location Membrane {ECO:0000305|PubMed:11911831, ECO:0000305|PubMed:11923219}; Single-pass type II membrane protein {ECO:0000305|PubMed:11911831, ECO:0000305|PubMed:11923219}.
Tissue Specificity Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon. {ECO:0000269|PubMed:11911831, ECO:0000269|PubMed:11923219, ECO:0000269|PubMed:9434163, ECO:0000269|PubMed:9872942}.
Top Pathways Cytokine-cytokine receptor interaction

Chicken TL1A protein fragment - ab90800 from Abcam

Category Protein
Prices $252.00
Sizes 25 µg
Source Yeast
Species Chicken

Human TL1A full length protein - ab107131 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE showing ab107131 (3µg).

Human TL1A peptide - ab41854 from Abcam

Category Peptide
Species Human

Human TL1A protein fragment - ab157061 from Abcam

Category Protein
Source E. coli
Species Human

Human TL1A protein fragment - ab50094 from Abcam

Category Protein
Source E. coli
Species Human

Human TL1A protein fragment - ab169880 from Abcam

Category Protein
Source E. coli
Species Human

Human TL1A protein fragment - ab182833 from Abcam

Category Protein
Source E. coli
Species Human

Mouse TL1A protein fragment - ab157011 from Abcam

Category Protein
Source HEK 293 cells
Species Mouse
SDS-PAGE analysis of ab157011. Lane 1: MW Marker Lane 2: 1µg ab157011 Banding observed beneath primary band is immunoreactive with anti-tag antibody.

TNFSF15 / TL1A / VEGI Antibody Blocking Peptide - LS-E1284 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

TNFSF15 / TL1A / VEGI Antibody Blocking Peptide - LS-E30012 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

Recombinant Human TL1A/TNFSF15 Protein - NBP2-35067 from Novus Biologicals

Category Protein
Prices $69.00, $169.00, $2,669.00
Sizes 5 µg, 20 µg, 1 mg
Source E. coli
Species Human

TL1A/TNFSF15 Recombinant Protein - H00009966-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

TL1A/TNFSF15 Partial Recombinant Protein - H00009966-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

TL1A/TNFSF15 Blocking Peptide - NBP1-76450PEP from Novus Biologicals

Category Peptide
Prices $129.00
Sizes 50 µg
Species Human

Recombinant Human TL1A/TNFSF15 Protein - NBP1-99602 from Novus Biologicals

Category Protein
Prices $295.00
Sizes 10 µg
Source E. coli
Species Human

TL1A/TNFSF15 Protein - NBP1-99776 from Novus Biologicals

Category Protein
Species Human

Recombinant Human TL1A/TNFSF15 Protein - NBP1-72297 from Novus Biologicals

Category Protein
Prices $269.00, $729.00
Sizes 100 µg, 500 µg
Source E. coli
Species Human

TNFSF15-Antibody-Center-Blocking-peptide - BP11879c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

TL1A Recombinant Protein (Active) - GTX48085-PRO from GeneTex

Category Protein
Prices $299.00
Sizes 20 μg
Source E. coli
Species Human

TL1A (Active) recombinant protein - GTX65483 from GeneTex

Category Protein
Prices $329.00
Sizes 10 μg
Source E. coli
Species Human

TL1A (Active) recombinant protein - GTX65482 from GeneTex

Category Protein
Prices $889.00
Sizes 50 μg
Source E. coli
Species Human

Recombinant Human TL1A/TNFSF15 - 1319-TL-010 from R&D Systems

Category Protein
Source E. coli-derived, Leu72-Leu251, with an N-terminal Met

Recombinant Human TL1A/TNFSF15, CF - 1319-TL-010/CF from R&D Systems

Category Protein
Source E. coli-derived, Leu72-Leu251, with an N-terminal Met

Human VEGI protein - orb180577 from Biorbyt

Category Protein
Prices $391.00
Sizes 10 μg
Source E. coli
Species Human

Human Vascular Endothelial Growth Inhibitor protein - orb80647 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 5 μg, 20 μg
Source E.coli
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