Faslg

Gene Symbol	Faslg
Entrez Gene	25385
Alt Symbol	Apt1Lg1, CD95-L, Fasl, Tnfsf6
Species	Rat
Gene Type	protein-coding
Description	Fas ligand (TNF superfamily, member 6)
Other Description	Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand)|CD95 ligand|CD95L protein|Fas antigen ligand|Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand)|Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand)|tumor necrosis factor ligand superfamily member 6
Swissprots	P36940
Accessions	EDM09413 P36940 AF104035 U03470 AAC52129 XM_006250148 XP_006250210 XM_008769607 XP_008767829 NM_012908 NP_037040
Function	Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects (By similarity). {ECO:0000250}.
Subcellular Location	FasL intracellular domain: Nucleus {ECO:0000250}. Note=The FasL ICD cytoplasmic form is translocated into the nucleus. {ECO:0000250}.
Tissue Specificity	Expressed in activated splenocytes and thymocytes. Moderate or weak expression found in small intestines, kidney and lung.
Top Pathways	Chagas disease (American trypanosomiasis), PI3K-Akt signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Herpes simplex infection, Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Fas Ligand (CD95L) Rat ELISA Kit - ab100759 from Abcam Category ELISA Kit Prices $499.00 Sizes 1 x 96 tests Sensitivity < 90 pg/ml Range 82.3 pg/ml - 60000 pg/ml

Rat Fas Ligand ELISA Kit - RAB0179 from Sigma-Aldrich Category ELISA Kit Prices $666.00 Sizes 1 kt

Factor-related Apoptosis ligand, FASL, Rat, ELISA Kit - CSB-E07325r from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 7.81 pg/ml Range 31.25 pg/ml-2000 pg/ml

Tumor necrosis factor ligand superfamily member 6, FASLG, Rat, ELISA Kit - E0031r from ARP American Research Products Category ELISA Kit Prices $496.00 Sizes 96 t Range 0.156-10 ng/mL

Faslg (Rat) ELISA Kit - KA1825 from Acris Antibodies Category ELISA Kit Prices $680.00 Sizes 1 kit

Rat FasL ELISA - ELR-FasL from RayBiotech Category ELISA Kit Prices $390.00, $702.00, $1,561.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit Sensitivity 90 pg/ml Range 90 pg/ml - 60000 pg/ml

Rat FASL ELISA Kit - RF0058 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Rat Faslg ELISA Kit - DEIA3435 from Creative Diagnostics Category ELISA Kit Sensitivity 90 pg/mL

Rat FASL/TNFSF6(Factor Related Apoptosis Ligand) ELISA Kit - E-EL-R2373 from Elabscience Category ELISA Kit Sensitivity 18.75 pg/mL Range 31.25—2000 pg/mL

Rat FASL (Factor Related Apoptosis Ligand) CLIA Kit - E-CL-R0749 from Elabscience Category CLIA Kit Sensitivity 7.50 pg/mL Range Average Recovery (%)

Rat CD178 ELISA Kit - CEK1583 from Cohesion Biosciences Category ELISA Kit Prices $360.00 Sizes 96 t Sensitivity 10 pg/ml Range 31.2 pg/ml - 2000 pg/ml

Rat FASL PicoKine™ ELISA Kit EK1110 - EK1110 from Boster Bio Category ELISA Kit Prices $369.00 Sizes 1 kit Sensitivity <10pg/ml Range 31.2pg/ml-2000pg/ml *This assay range is determined using common samples. For samples with low target protein concentrations, users can adjust the standard curve to extend the lower limit of assay range.

Rat Factor-related Apoptosis ligand,FASL ELISA Kit - CSB-E07325r from Cusabio Category ELISA Kit Sensitivity 7.8 pg/ml Range 31.25 pg/ml-2000 pg/ml

Rat FAS Ligand ELISA - E02F0051 from BlueGene Biotech Category ELISA Kit Sensitivity 0.1 ng/mL

ELISA Kit for Factor Related Apoptosis Ligand (FASL) - SEA031Ra from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 3.4pg/mL. Range 7.813-500pg/mL The standard curve concentrations used for the ELISA's were 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL, 15.625pg/mL, 7.813pg/mL

FASLG - KBB-281 from Nordic BioSite Sensitivity <10pg/ml Range 31.2pg/ml-2000pg/ml

Rat FASL/TNFSF6(Factor Related Apoptosis Ligand) ELISA Kit - E-EL-R2373 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 18.75 pg/mL Range 31.25~2000 pg/mL

Rat FASL (Factor Related Apoptosis Ligand) CLIA Kit - E-CL-R0749 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

Rat FASL ELISA Kit - abx054106 from Abbexa Category ELISA Kit Sensitivity 0.5 pg/ml Range 1.5 pg/ml - 100 pg/ml

Rat Tumor necrosis factor ligand superfamily member 6 ELISA Kit - abx255668 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

Factor Related Apoptosis Ligand (FASL), Rat, ELISA Kit - DL-FASL-Ra from ARP American Research Products Category ELISA Kit Prices $715.00 Sizes 96 t Range 0.312-20 ng/mL

FasL, ELISA Kit - MBS843388 from MyBioSource Category ELISA Kit Prices $815.00 Sizes 100 assays

FASL (Factor Related Apoptosis Ligand), CLIA Kit - MBS2532103 from MyBioSource Category CLIA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 7.5pg/mL Range 12.5-800pg/mL

Rat FAS-L ELISA Kit - EA100651 from Acris Antibodies Category ELISA Kit Prices $389.00 Sizes 1 kit Range 10

FAS-L ELISA Kit (Rat) (OKBB00494) - OKBB00494 from Aviva Systems Biology Category ELISA Kit Prices $385.00 Sizes 96 wells Sensitivity <= 10 pg/mL Range 31.2 pg/mL-2,000 pg/mL

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