Faslg

Gene Symbol	Faslg
Entrez Gene	25385
Alt Symbol	Apt1Lg1, CD95-L, Fasl, Tnfsf6
Species	Rat
Gene Type	protein-coding
Description	Fas ligand (TNF superfamily, member 6)
Other Description	Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand)|CD95 ligand|CD95L protein|Fas antigen ligand|Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand)|Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand)|tumor necrosis factor ligand superfamily member 6
Swissprots	P36940
Accessions	EDM09413 P36940 AF104035 U03470 AAC52129 XM_006250148 XP_006250210 XM_008769607 XP_008767829 NM_012908 NP_037040
Function	Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects (By similarity). {ECO:0000250}.
Subcellular Location	FasL intracellular domain: Nucleus {ECO:0000250}. Note=The FasL ICD cytoplasmic form is translocated into the nucleus. {ECO:0000250}.
Tissue Specificity	Expressed in activated splenocytes and thymocytes. Moderate or weak expression found in small intestines, kidney and lung.
Top Pathways	Chagas disease (American trypanosomiasis), PI3K-Akt signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Herpes simplex infection, Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Recombinant Rat Fas Ligand/TNFSF6 - 1614-FL-025 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Leu104-Leu278, with an N-terminal 7-His tag

Recombinant Rat Fas Ligand/TNFSF6, CF - 1614-FL-025/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Leu104-Leu278, with an N-terminal 7-His tag

Rat FASL Protein - abx066485 from Abbexa Category Protein Source E.coli Species Rat

Factor Related Apoptosis Ligand (FASL), Rat - 20-6092 from ARP American Research Products Category Protein Prices $525.00 Sizes 50 µg Source E.coli Species Rat

Recombinant Factor Related Apoptosis Ligand (FASL) - RPA031Ra01 from Cloud-clone Category Protein Source E.coli Species Rat

Recombinant Rat Tumor necrosis factor ligand superfamily member 6(Faslg) - CSB-YP008434RA CSB-EP008434RA CSB-BP008434RA CSB-MP008434RA from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Rat

Recombinant Rat Fas Ligand/TNFSF6 Protein - 1614-FL from R&D Systems Category Protein Prices $339.00 Sizes 25 µg Source Mouse myeloma cell line, NS0-derived Leu104-Leu278, with an N-terminal 7-His tag Species Rat

Recombinant Rat Fas Ligand/TNFSF6 Protein, CF - 1614-FL/CF from R&D Systems Category Protein Prices $339.00 Sizes 25 µg Source Mouse myeloma cell line, NS0-derived Leu104-Leu278, with an N-terminal 7-His tag Species Rat

Recombinant Rat FASLG Protein - FASLG-2274R from Creative Biomart Category Protein Source Mammalian Cells Species Rat

Factor Related Apoptosis Ligand (FASL), Recombinant Protein - MBS2011418 from MyBioSource Category Protein Prices $190.00, $410.00, $630.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Rat

FASLG Recombinant Protein (OPCD03091) - OPCD03091 from Aviva Systems Biology Category Protein Source E.coli Species Rat

Recombinant Rat Faslg Protein, His-tagged - Faslg-373R from Creative Biomart Category Protein Source Yeast Species Rat

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