PDE5A

Gene Symbol	PDE5A
Entrez Gene	8654
Alt Symbol	CGB-PDE, CN5A, PDE5
Species	Human
Gene Type	protein-coding
Description	phosphodiesterase 5A, cGMP-specific
Other Description	cGMP-binding cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase|cGMP-specific 3',5'-cyclic phosphodiesterase|cGMP-specific phosphodiesterase PDE5A2|cGMP-specific phosphodiesterase type 5A|phosphodiesterase isozyme 5
Swissprots	Q86UI0 O75887 O75026 A0AV69 Q86V66 O76074 Q9Y6Z6 A8K2C4
Accessions	AAF40301 AAF40302 AAK08016 AAY40985 BAA33372 EAX05275 EAX05276 EAX05277 EAX05278 O76074 AB015656 BAA81667 AF043731 AAC63967 AF043732 AAC63968 AF155192 AAF40303 AF155193 AAF40304 AF155194 AAF40305 AJ004865 CAA06170 AK290189 BAF82878 AM392687 CAL37565 AM392735 CAL37613 AM392945 CAL37823 AM393036 CAL37914 AM393171 CAL38049 AM393270 CAL38148 AM393311 CAL38189 AM393426 CAL38304 AM393432 CAL38310 AM393448 CAL38326 AM393814 CAL38689 AY264918 AAP21809 AY266363 AAP31235 BC126233 AAI26234 BM920622 BM978332 CD511199 JQ286346 AEW91484 NM_001083 NP_001074 NM_033430 NP_236914 NM_033437 NP_246273
Function	Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'- GMP.
Tissue Specificity	Expressed in aortic smooth muscle cells, heart, placenta, skeletal muscle and pancreas and, to a much lesser extent, in brain, liver and lung.
Top Pathways	cGMP-PKG signaling pathway, Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human PDE5A full length protein - ab56614 from Abcam Category Protein Prices $466.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Active human PDE5A protein fragment - ab125581 from Abcam Category Protein Prices $302.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Human

Active mouse PDE5A full length protein - ab80330 from Abcam Category Protein Prices $466.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Mouse

Human PDE5A peptide - ab66454 from Abcam Category Peptide

Human PDE5A protein fragment - ab152901 from Abcam Category Protein Source Wheat germ Species Human

PDE5A peptide (864-875) - ab45684 from Abcam Category Peptide Species Human

Recombinant Human PDE5A Protein - H00008654-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PDE5A blocking peptide - GTX89598-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog, Rat, Bovine

PDE5A Peptide - AC21-0659-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PDE5A - H00008654-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PDE5A - H00008654-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PDE5A Control Peptide - AP10239CP-N from Acris Antibodies Category Peptide Prices $235.00 Sizes 250 µg

PDE5A control peptide - AP10240CP-N from Acris Antibodies Category Peptide Prices $235.00 Sizes 250 µg

PDE5A Peptide - 46-153P from ProSci Category Peptide Species Human

PDE5A fusion protein - Ag18779 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

PDE5A fusion protein - ag18963 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli-derived, PET28a Species Human

PDE5A1, Active Human Recombinant Protein - GWB-9C8952 from Genway Biotech Category Protein Prices $600.00 Sizes 10 µg Species Human

Recombinant Human PDE5A, GST-tagged, Active - PDE5A-479H from Creative Biomart Category Protein Source Sf9 insect cells using baculovirus.

Recombinant Human PDE5A, GST-tagged - PDE5A-1603H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human PDE5A, His-tagged - PDE5A-476H from Creative Biomart Category Protein Source Sf9 insect cells Species Human

Recombinant Human PDE5A - PDE5A-636H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Phosphodiesterase 5A, cGMP Specific (PDE5A) - RPF645Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Phosphodiesterase 5A, cGMP Specific (PDE5A) - RPF645Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human cGMP-specific 3',5'-cyclic phosphodiesterase(PDE5A) ,partial - CSB-YP524921HU CSB-EP524921HU CSB-BP524921HU CSB-MP524921HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PDE5A (transcript variant 2) - TP318974 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

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