PDE5A

Gene Symbol PDE5A
Entrez Gene 8654
Alt Symbol CGB-PDE, CN5A, PDE5
Species Human
Gene Type protein-coding
Description phosphodiesterase 5A, cGMP-specific
Other Description cGMP-binding cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase|cGMP-specific 3',5'-cyclic phosphodiesterase|cGMP-specific phosphodiesterase PDE5A2|cGMP-specific phosphodiesterase type 5A|phosphodiesterase isozyme 5
Swissprots Q86UI0 O75887 O75026 A0AV69 Q86V66 O76074 Q9Y6Z6 A8K2C4
Accessions AAF40301 AAF40302 AAK08016 AAY40985 BAA33372 EAX05275 EAX05276 EAX05277 EAX05278 O76074 AB015656 BAA81667 AF043731 AAC63967 AF043732 AAC63968 AF155192 AAF40303 AF155193 AAF40304 AF155194 AAF40305 AJ004865 CAA06170 AK290189 BAF82878 AM392687 CAL37565 AM392735 CAL37613 AM392945 CAL37823 AM393036 CAL37914 AM393171 CAL38049 AM393270 CAL38148 AM393311 CAL38189 AM393426 CAL38304 AM393432 CAL38310 AM393448 CAL38326 AM393814 CAL38689 AY264918 AAP21809 AY266363 AAP31235 BC126233 AAI26234 BM920622 BM978332 CD511199 JQ286346 AEW91484 NM_001083 NP_001074 NM_033430 NP_236914 NM_033437 NP_246273
Function Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'- GMP.
Tissue Specificity Expressed in aortic smooth muscle cells, heart, placenta, skeletal muscle and pancreas and, to a much lesser extent, in brain, liver and lung.
Top Pathways cGMP-PKG signaling pathway, Purine metabolism

PDE5A CRISPR/Cas9 KO Plasmid (h) - sc-401627 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDE5A HDR Plasmid (h) - sc-401627-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDE5A Double Nickase Plasmid (h) - sc-401627-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDE5A Double Nickase Plasmid (h2) - sc-401627-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDE5A CRISPR Activation Plasmid (h) - sc-401627-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDE5A CRISPR Activation Plasmid (h2) - sc-401627-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDE5A Lentiviral Activation Particles (h) - sc-401627-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDE5A Lentiviral Activation Particles (h2) - sc-401627-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDE5A siRNA (h) - sc-44918 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PDE5A shRNA Plasmid (h) - sc-44918-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PDE5A shRNA (h) Lentiviral Particles - sc-44918-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PDE5A RNAi - H00008654-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

PDE5A RNAi - H00008654-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

PDE5A RNAi - H00008654-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN16541 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16541 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PDE5A siRNA (Human) - CRH5691 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Pde5a (NM_001083.3) - SHH372488 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PDE5A(NM_033430.2) - SHG172765 from Creative biogene

Category siRNA
Species Reactivities Human

Human PDE5A siRNA - orb266193 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PDE5A shRNA Plasmid (Human) - CHH5691 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PDE5A miRNA 3'UTR clone - MiUTR1H-07714 from Creative biogene

Species Reactivities Human

PDE5A miRNA 3'UTR clone - MiUTR4H-TG12101 from Creative biogene

Species Reactivities Human
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