PPP1R1A

Gene Symbol	PPP1R1A
Entrez Gene	5502
Alt Symbol	I1, IPP1
Species	Human
Gene Type	protein-coding
Description	protein phosphatase 1, regulatory (inhibitor) subunit 1A
Other Description	I-1|IPP-1|inhibitor-1|protein phosphatase 1 regulatory subunit 1A|protein phosphatase inhibitor 1|protein phosphatase inhibitor-1
Swissprots	Q6IB01 Q13522 Q8WWV2 Q8TBJ2
Accessions	EAW96792 Q13522 AK123969 BAC85737 AY063766 AAL48321 BC022470 AAH22470 BM876308 BP211831 CR457003 CAG33284 U48707 AAB02402 XM_005268995 XP_005269052 XM_006719471 XP_006719534 XM_011538521 XP_011536823 XM_011538522 XP_011536824 NM_006741 NP_006732
Function	Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
Top Pathways	Long-term potentiation, Adrenergic signaling in cardiomyocytes

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IPP-1 CRISPR/Cas9 KO Plasmid (h) - sc-402634 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IPP-1 HDR Plasmid (h) - sc-402634-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IPP-1 Double Nickase Plasmid (h) - sc-402634-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IPP-1 Double Nickase Plasmid (h2) - sc-402634-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IPP-1 CRISPR Activation Plasmid (h) - sc-402634-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IPP-1 CRISPR Activation Plasmid (h2) - sc-402634-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IPP-1 Lentiviral Activation Particles (h) - sc-402634-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IPP-1 Lentiviral Activation Particles (h2) - sc-402634-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IPP-1 siRNA (h) - sc-45873 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

IPP-1 shRNA Plasmid (h)-SH - sc-45873-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

IPP-1 shRNA (h) Lentiviral Particles - sc-45873-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU022211 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP0566 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0565 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0567 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN17272 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17272 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08321 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr08321

PPP1R1A siRNA (Human) - CRH3687 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human PPP1R1A (NM_006741.3) - SHH381160 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PPP1R1A(NM_006741.3) - SHR133656 from Creative biogene Category siRNA Species Reactivities Human

Human PPP1R1A siRNA - orb264189 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PPP1R1A shRNA Plasmid (Human) - CHH3687 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

PPP1R1A miRNA 3'UTR clone - MiUTR1H-08182 from Creative biogene Species Reactivities Human

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