Gene Symbol | PPP1R1A |
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Entrez Gene | 5502 |
Alt Symbol | I1, IPP1 |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
Other Description | I-1|IPP-1|inhibitor-1|protein phosphatase 1 regulatory subunit 1A|protein phosphatase inhibitor 1|protein phosphatase inhibitor-1 |
Swissprots | Q6IB01 Q13522 Q8WWV2 Q8TBJ2 |
Accessions | EAW96792 Q13522 AK123969 BAC85737 AY063766 AAL48321 BC022470 AAH22470 BM876308 BP211831 CR457003 CAG33284 U48707 AAB02402 XM_005268995 XP_005269052 XM_006719471 XP_006719534 XM_011538521 XP_011536823 XM_011538522 XP_011536824 NM_006741 NP_006732 |
Function | Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. |
Top Pathways | Long-term potentiation, Adrenergic signaling in cardiomyocytes |
IPP-1 (N-17) - sc-7731 from Santa Cruz Biotechnology
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IPP-1 (N-20) - sc-14260 from Santa Cruz Biotechnology
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IPP-1 (T-20) - sc-14261 from Santa Cruz Biotechnology
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IPP-1 (C-18) - sc-7730 from Santa Cruz Biotechnology
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p-IPP-1 (Ser 67) - sc-14268 from Santa Cruz Biotechnology
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p-IPP-1 (Thr 35) - sc-14267 from Santa Cruz Biotechnology
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Anti-Protein phosphatase inhibitor 1 antibody [EP902Y] - ab40877 from Abcam
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Anti-PPP1R1A / IPP1 Antibody (aa50-100) IHC-plus⢠- LS-B1799 from LifeSpan Bioscience
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Anti-PPP1R1A / IPP1 Antibody - LS-C342147 from LifeSpan Bioscience
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Anti-PPP1R1A / IPP1 Antibody (N-Terminus) - LS-C146325 from LifeSpan Bioscience
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Anti-PPP1R1A / IPP1 Antibody (aa1-100, clone EP902Y) - LS-C49712 from LifeSpan Bioscience
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Protein Phosphatase inhibitor 1 Antibody (EP902Y) - NB110-57125 from Novus Biologicals
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Protein Phosphatase inhibitor 1 Antibody - NBP2-24490 from Novus Biologicals
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Protein Phosphatase inhibitor 1 Antibody - NBP1-39750 from Novus Biologicals
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Protein Phosphatase inhibitor 1 Antibody - NBP2-37895 from Novus Biologicals
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Anti-PPP1R1A (41-55) antibody produced in rabbit - R6906 from Sigma-Aldrich
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Anti-PPP1R1A (148-160) antibody produced in rabbit - R7031 from Sigma-Aldrich
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IPP-1-Antibody - AJ1410a from Abgent, a WuXi AppTec company
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PPP1R1A Antibody (OALA02151) - OALA02151 from Aviva Systems Biology
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PPP1R1A (50-100) antibody - AP08281PU-N from Acris Antibodies
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Rabbit Anti-Human PPP1R1A / IPP1 (aa50-100) - 119-12419 from RayBiotech
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PPP1R1A Antibody - 48-938 from ProSci
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PPP1R1A antibody - 12461-1-AP from Proteintech Group
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IPP-1 - MBS602532 from MyBioSource
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Protein Phosphatase-1 Inhibitor (PPP1R1A) Rabbit anti-Human Polyclonal (aa50-100) Antibody - GWB-AB7C53 from Genway Biotech
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