SLC5A7

Gene Symbol SLC5A7
Entrez Gene 60482
Alt Symbol CHT, CHT1, HMN7A, hCHT
Species Human
Gene Type protein-coding
Description solute carrier family 5 (sodium/choline cotransporter), member 7
Other Description hemicholinium-3-sensitive choline transporter|high affinity choline transporter 1|high affinity choline transporter; hemicholinium-3-sensitive choline transporter|solute carrier family 5 (choline transporter), member 7|solute carrier family 5 member 7
Swissprots Q53TF2 Q9GZV3
Accessions AAY14927 CAC88115 EAW53893 Q9GZV3 AB043997 BAB18161 AB084377 AF276871 AAG25940 AJ401466 CAC03717 AK300801 BAG62459 AK315280 BAG37689 BC111524 AAI11525 BC111525 AAI11526 DA714970 XM_011511579 XP_011509881 XM_011511580 XP_011509882 XM_011511581 XP_011509883 NM_001305005 NP_001291934 NM_001305006 NP_001291935 NM_001305007 NP_001291936 NM_021815 NP_068587
Function Imports choline from the extracellular space to the neuron with high affinity. Choline uptake is the rate-limiting step in acetylcholine synthesis. Sodium ion- and chloride ion- dependent. {ECO:0000269|PubMed:11027560}.
Subcellular Location Membrane {ECO:0000269|PubMed:11027560}; Multi-pass membrane protein {ECO:0000269|PubMed:11027560}.
Tissue Specificity Expressed in putamen, spinal cord and medulla. Specific for cholinergic neurons.
Top Pathways Choline metabolism in cancer

SLC5A7 / Choline Transporter Antibody Blocking Peptide - LS-E16178 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SLC5A7-Antibody-C-term-Blocking-Peptide - BP16408b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

SLC5A7 Blocking Peptide - 33R-1884 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

SLC5A7 fusion protein - Ag16136 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

SLC5A7 fusion protein - ag17630 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human SLC5A7, GST-tagged - SLC5A7-2779H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human SLC5A7 - SLC5A7-904H from Creative Biomart

Category Protein
Source Mammalian Cells
Species Human

Recombinant High Affinity Choline Transporter (ChT) - RPE387Ra01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Rat

SLC5A7 Protein - abx163162 from Abbexa

Category Protein
Species Human

SLC5A7 Peptide, Human - M34GP14620H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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