SLC5A7

Gene Symbol SLC5A7
Entrez Gene 60482
Alt Symbol CHT, CHT1, HMN7A, hCHT
Species Human
Gene Type protein-coding
Description solute carrier family 5 (sodium/choline cotransporter), member 7
Other Description hemicholinium-3-sensitive choline transporter|high affinity choline transporter 1|high affinity choline transporter; hemicholinium-3-sensitive choline transporter|solute carrier family 5 (choline transporter), member 7|solute carrier family 5 member 7
Swissprots Q53TF2 Q9GZV3
Accessions AAY14927 CAC88115 EAW53893 Q9GZV3 AB043997 BAB18161 AB084377 AF276871 AAG25940 AJ401466 CAC03717 AK300801 BAG62459 AK315280 BAG37689 BC111524 AAI11525 BC111525 AAI11526 DA714970 XM_011511579 XP_011509881 XM_011511580 XP_011509882 XM_011511581 XP_011509883 NM_001305005 NP_001291934 NM_001305006 NP_001291935 NM_001305007 NP_001291936 NM_021815 NP_068587
Function Imports choline from the extracellular space to the neuron with high affinity. Choline uptake is the rate-limiting step in acetylcholine synthesis. Sodium ion- and chloride ion- dependent. {ECO:0000269|PubMed:11027560}.
Subcellular Location Membrane {ECO:0000269|PubMed:11027560}; Multi-pass membrane protein {ECO:0000269|PubMed:11027560}.
Tissue Specificity Expressed in putamen, spinal cord and medulla. Specific for cholinergic neurons.
Top Pathways Choline metabolism in cancer

CHT1 CRISPR/Cas9 KO Plasmid (h) - sc-404869 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHT1 HDR Plasmid (h) - sc-404869-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHT1 Double Nickase Plasmid (h) - sc-404869-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHT1 Double Nickase Plasmid (h2) - sc-404869-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHT1 CRISPR Activation Plasmid (h) - sc-404869-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHT1 CRISPR Activation Plasmid (h2) - sc-404869-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHT1 Lentiviral Activation Particles (h) - sc-404869-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHT1 Lentiviral Activation Particles (h2) - sc-404869-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHT1 siRNA (h) - sc-44594 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CHT1 shRNA Plasmid (h) - sc-44594-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CHT1 shRNA (h) Lentiviral Particles - sc-44594-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU000431 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19667 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19667 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SLC5A7 siRNA (Human) - CRJ1797 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CHT1 RNAi - H00060482-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SLC5A7 - MBS8237517 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SLC5A7 (NM_021815.2) - SHH411764 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SLC5A7(NM_021815.2) - SHL010774 from Creative biogene

Category siRNA
Species Reactivities Human

Human SLC5A7 siRNA - orb272298 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC5A7 shRNA Plasmid (Human) - CHJ1797 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC5A7 miRNA 3'UTR clone - MiUTR1H-09588 from Creative biogene

Species Reactivities Human
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