SLC27A2

Gene Symbol	SLC27A2
Entrez Gene	11001
Alt Symbol	ACSVL1, FACVL1, FATP2, HsT17226, VLACS, VLCS, hFACVL1
Species	Human
Gene Type	protein-coding
Description	solute carrier family 27 (fatty acid transporter), member 2
Other Description	FATP-2\|THCA-CoA ligase\|fatty acid transport protein 2\|fatty-acid-coenzyme A ligase, very long-chain 1\|long-chain-fatty-acid--CoA ligase\|solute carrier family 27 member 2\|very long-chain acyl-CoA synthetase\|very long-chain fatty-acid-coenzyme A ligase 1\|very long-chain-fatty-acid-CoA ligase\|very-long-chain acyl-CoA synthetase
Swissprots	O14975 Q6PF09 Q53FY6 A8K2J7
Accessions	EAW77384 EAW77385 EAW77386 O14975 AF096290 AAC64973 AK123905 BAG53981 AK222859 BAD96579 AK223145 BAD96865 AK290262 BAF82951 BC057770 AAH57770 BM980042 D88308 BAA23644 NM_001159629 NP_001153101 NM_003645 NP_003636
Function	Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity). {ECO:0000250}.
Subcellular Location	Endoplasmic reticulum membrane; Multi-pass membrane protein. Peroxisome membrane; Multi-pass membrane protein. Note=Peripheral membrane associated with the lumenal side of peroxisomes.
Tissue Specificity	Expressed in liver, kidney, placenta and pancreas. {ECO:0000269\|PubMed:10198260}.
Top Pathways	PPAR signaling pathway, Peroxisome

ACSVL1 (D-7) - sc-393906 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

ACSVL1 (D-7): sc-393906. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

ACSVL1 (F-12) - sc-161310 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

ACSVL1 (H-127) - sc-367655 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

ACSVL1 (N-14) - sc-161311 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

ACSVL1 (N-14): sc-161311. Western blot analysis of ACSVL1 expression in KNRK whole cell lysate.

Anti-FATP2 antibody - ab83763 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-FATP2 antibody - ab85801 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-FATP2 antibody (ab85801) at 1 µg/mlLane 1 : Liver (Human) Tissue Lysate - adult normal tissue (ab29889)Lane 2 : Kidney (Human) Tissue Lysate - adult normal tissue (ab30203)Lane 3 : Placenta (Human) Tissue Lysate - adult normal tissue (ab29745)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-FATP2 antibody [6B3A9] - ab175373 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	6B3A9

All lanes : Anti-FATP2 antibody [6B3A9] (ab175373) at 1/500 dilutionLane 1 : Non transfected HEK293 cell lysateLane 2 : FATP2 (aa: 346-405)-hIgGFc transfected HEK293 cell lysate

FATP2/SLC27A2 Antibody (6B3A9) - NBP2-37738 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	6B3A9

FATP2/SLC27A2 Antibody (466106) [Unconjugated] - MAB4659 from Novus Biologicals

Prices	$99.00, $249.00
Sizes	25 µg, 100 µg
Host	Mouse
Clonality	Monoclonal
Clone	466106

HepG2 human hepatocellular carcinoma cell line was stained with Mouse Anti-Human FATP2 Monoclonal Antibody (Catalog # MAB4659, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG F(ab')2 Secondary Antibody (Catalog # F0102B). To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin.

SLC27A2/ACSVL1 Polyclonal Antibody - bs-3936R from Bioss

Prices	$269.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Formalin-fixed and paraffin embedded human colorectal cancer labeled with Anti SLC27A2 Polyclonal Antibody, Unconjugated (bs-3936R) followed by conjugation to the secondary antibody and DAB staining

Anti-SLC27A2 antibody produced in rabbit - SAB2102193 from Sigma-Aldrich

Prices	$347.50, $347.50
Sizes	50 µg, 100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-SLC27A2: <B>Cat. No. SAB2102193</B>: Immunohistochemistry of SLC27A2 in Human Liver tissue with SLC27A2 antibody at 10 μg/mL.

Anti-SLC27A2 antibody produced in rabbit - HPA026089 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-SLC27A2: <B>Cat. No. HPA026089</B>: Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.

Monoclonal Anti-SLC27A2 antibody produced in mouse - SAB1403096 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	1F1

<B>Immunofluorescence</B><BR/>Monoclonal Anti-SLC27A2: <B>Cat. No. SAB1403096</B>: Antibody concentration: 10 μg/mL using HeLa cell.

SLC27A2 antibody - N-terminal region (ARP43855_P050) - ARP43855_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

NT5E-Antibody - AO1910a from Abgent, a WuXi AppTec company

Prices	$385.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	4G6B10

Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Human FATP2 Antibody - MAB4659 from R&D Systems

Prices	$99.00, $249.00
Sizes	25 µg, 100 µg
Host	Mouse
Clone	466106

Detection of FATP2 in HepG2 Human Cell Line by Flow Cytometry. HepG2 human hepatocellular carcinoma cell line was stained with Mouse Anti-Human FATP2 Monoclonal Antibody (Catalog # MAB4659, filled histogram) or isotype control antibody (Catalog # MAB002 , open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG F(ab') 2 Secondary Antibody (Catalog # F0102B ). To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin.

Human FATP2 MAb (Clone 466106), Mouse IgG1 - MAB4659-SP from R&D Systems

Host	Mouse
Clonality	Monoclonal
Clone	466106

SLC27A2 antibody - orb6972 from Biorbyt

Prices	$60.00, $128.00, $170.00, $255.00, $340.00
Sizes	5 μg (Trial size), 20 μg (Trial size), 50 μg, 100 μg, 200 μg
Host	Rabbit
Clonality	Polyclonal

IHC-P of human colon cancer using SLC27A2 antibody.

SLC27A2 antibody - 70R-7262 from Fitzgerald

Prices	$345.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

SLC27A2 antibody - 70R-20336 from Fitzgerald

Prices	$375.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

SLC27A2 Polyclonal Antibody - A1077 from ABclonal

Prices	$130.00, $220.00, $380.00
Sizes	50 µl, 100 µl, 200 µl
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of HepG2 cell lysate using SLC27A2 antibody.

SLC27A2/ACSVL1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-3936R-A350 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SLC27A2/ACSVL1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-3936R-A488 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SLC27A2/ACSVL1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-3936R-A555 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SLC27A2/ACSVL1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-3936R-A647 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

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