SLC27A2

Gene Symbol SLC27A2
Entrez Gene 11001
Alt Symbol ACSVL1, FACVL1, FATP2, HsT17226, VLACS, VLCS, hFACVL1
Species Human
Gene Type protein-coding
Description solute carrier family 27 (fatty acid transporter), member 2
Other Description FATP-2|THCA-CoA ligase|fatty acid transport protein 2|fatty-acid-coenzyme A ligase, very long-chain 1|long-chain-fatty-acid--CoA ligase|solute carrier family 27 member 2|very long-chain acyl-CoA synthetase|very long-chain fatty-acid-coenzyme A ligase 1|very long-chain-fatty-acid-CoA ligase|very-long-chain acyl-CoA synthetase
Swissprots O14975 Q6PF09 Q53FY6 A8K2J7
Accessions EAW77384 EAW77385 EAW77386 O14975 AF096290 AAC64973 AK123905 BAG53981 AK222859 BAD96579 AK223145 BAD96865 AK290262 BAF82951 BC057770 AAH57770 BM980042 D88308 BAA23644 NM_001159629 NP_001153101 NM_003645 NP_003636
Function Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity). {ECO:0000250}.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Peroxisome membrane; Multi-pass membrane protein. Note=Peripheral membrane associated with the lumenal side of peroxisomes.
Tissue Specificity Expressed in liver, kidney, placenta and pancreas. {ECO:0000269|PubMed:10198260}.
Top Pathways PPAR signaling pathway, Peroxisome

ACSVL1 CRISPR/Cas9 KO Plasmid (h) - sc-405122 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACSVL1 HDR Plasmid (h) - sc-405122-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACSVL1 Double Nickase Plasmid (h) - sc-405122-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACSVL1 Double Nickase Plasmid (h2) - sc-405122-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACSVL1 CRISPR Activation Plasmid (h) - sc-405122-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACSVL1 CRISPR Activation Plasmid (h2) - sc-405122-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACSVL1 Lentiviral Activation Particles (h) - sc-405122-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACSVL1 Lentiviral Activation Particles (h2) - sc-405122-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACSVL1 siRNA (h) - sc-90127 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ACSVL1 shRNA Plasmid (h) - sc-90127-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ACSVL1 shRNA (h) Lentiviral Particles - sc-90127-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FATP2/SLC27A2 RNAi - H00011001-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU051771 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19532 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19532 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SLC27A2 siRNA (Human) - CRH7513 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC27A2 - MBS828169 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SLC27A2 (NM_003645.3) - SHH410052 from Creative biogene

Category siRNA
Species Reactivities Human

Human SLC27A2 siRNA - orb268015 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC27A2 shRNA Plasmid (Human) - CHH7513 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC27A2 miRNA 3'UTR clone - MiUTR3H-05802 from Creative biogene

Species Reactivities Human

SLC27A2 miRNA 3'UTR clone - MiUTR3H-05803 from Creative biogene

Species Reactivities Human
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