Gene Symbol | CPSF4 |
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Entrez Gene | 10898 |
Alt Symbol | CPSF30, NAR, NEB1 |
Species | Human |
Gene Type | protein-coding |
Description | cleavage and polyadenylation specific factor 4, 30kDa |
Other Description | CPSF 30 kDa subunit|NS1 effector domain-binding protein 1|cleavage and polyadenylation specificity factor 30 kDa subunit|cleavage and polyadenylation specificity factor subunit 4|cleavage-polyadenylation specificity factor, 30kD|neb-1|no arches homolog|no arches-like zinc finger protein |
Swissprots | Q86TF8 O95639 Q6FGE6 D6W5S8 Q9BTW6 |
Accessions | ABN05292 EAL23878 EAW76662 EAW76663 EAW76664 EAW76665 EAW76666 EAW76667 EAW76668 O95639 AA040394 AI076832 AK301745 BAH13546 BC003101 AAH03101 BC050738 AAH50738 BM757197 BM787372 BQ052009 BQ641871 CR542161 CAG46958 CX754488 HQ448622 ADQ33100 U79569 AAD00321 XM_011515755 XP_011514057 XM_011515756 XP_011514058 XM_011515757 XP_011514059 XM_011515758 XP_011514060 XM_011515759 XP_011514061 NM_001081559 NP_001075028 NM_006693 NP_006684 |
Function | Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U). {ECO:0000269|PubMed:14749727, ECO:0000269|PubMed:9224719}. |
Subcellular Location | Nucleus. |
Top Pathways | mRNA surveillance pathway, Influenza A |
CPSF4 (A-11) - sc-393316 from Santa Cruz Biotechnology
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CPSF4 (D-1) - sc-390516 from Santa Cruz Biotechnology
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CPSF4 (D-9) - sc-390643 from Santa Cruz Biotechnology
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CPSF4 (K-17) - sc-79418 from Santa Cruz Biotechnology
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CPSF4 (G-14) - sc-79417 from Santa Cruz Biotechnology
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CPSF4 (E-25) - sc-133480 from Santa Cruz Biotechnology
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CPSF4 (H-102) - sc-366244 from Santa Cruz Biotechnology
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Anti-CPSF30 antibody - ab198219 from Abcam
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Anti-CPSF30 antibody - ab103142 from Abcam
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Anti-CPSF30 antibody [2202C1] - ab51343 from Abcam
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Anti-CPSF30 antibody [EPR7433] - ab131218 from Abcam
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Anti-NAR / CPSF4 Antibody (N-Terminus) - LS-C144913 from LifeSpan Bioscience
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Anti-NAR / CPSF4 Antibody - LS-C79402 from LifeSpan Bioscience
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Anti-NAR / CPSF4 Antibody (clone 2202C1) - LS-C184415 from LifeSpan Bioscience
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Anti-NAR / CPSF4 Antibody (aa96-123, AP) - LS-C208600 from LifeSpan Bioscience
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Anti-NAR / CPSF4 Antibody (aa96-123, APC) - LS-C208601 from LifeSpan Bioscience
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Anti-NAR / CPSF4 Antibody (Internal, clone EPR7433) - LS-C154590 from LifeSpan Bioscience
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Anti-NAR / CPSF4 Antibody (C-Terminus) - LS-C30443 from LifeSpan Bioscience
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Anti-NAR / CPSF4 Antibody (aa96-123, Biotin) - LS-C208602 from LifeSpan Bioscience
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Anti-NAR / CPSF4 Antibody (aa96-123, FITC) - LS-C208603 from LifeSpan Bioscience
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Anti-NAR / CPSF4 Antibody (aa96-123, PE) - LS-C208605 from LifeSpan Bioscience
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Anti-NAR / CPSF4 Antibody (aa220-245) - LS-C288375 from LifeSpan Bioscience
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Anti-NAR / CPSF4 Antibody (aa96-123, Azide-free, HRP) - LS-C208604 from LifeSpan Bioscience
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Anti-NAR / CPSF4 Antibody (aa245-269) - LS-C288377 from LifeSpan Bioscience
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Anti-NAR / CPSF4 Antibody - LS-C307075 from LifeSpan Bioscience
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