Gene Symbol | CPSF4 |
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Entrez Gene | 10898 |
Alt Symbol | CPSF30, NAR, NEB1 |
Species | Human |
Gene Type | protein-coding |
Description | cleavage and polyadenylation specific factor 4, 30kDa |
Other Description | CPSF 30 kDa subunit|NS1 effector domain-binding protein 1|cleavage and polyadenylation specificity factor 30 kDa subunit|cleavage and polyadenylation specificity factor subunit 4|cleavage-polyadenylation specificity factor, 30kD|neb-1|no arches homolog|no arches-like zinc finger protein |
Swissprots | Q86TF8 O95639 Q6FGE6 D6W5S8 Q9BTW6 |
Accessions | ABN05292 EAL23878 EAW76662 EAW76663 EAW76664 EAW76665 EAW76666 EAW76667 EAW76668 O95639 AA040394 AI076832 AK301745 BAH13546 BC003101 AAH03101 BC050738 AAH50738 BM757197 BM787372 BQ052009 BQ641871 CR542161 CAG46958 CX754488 HQ448622 ADQ33100 U79569 AAD00321 XM_011515755 XP_011514057 XM_011515756 XP_011514058 XM_011515757 XP_011514059 XM_011515758 XP_011514060 XM_011515759 XP_011514061 NM_001081559 NP_001075028 NM_006693 NP_006684 |
Function | Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U). {ECO:0000269|PubMed:14749727, ECO:0000269|PubMed:9224719}. |
Subcellular Location | Nucleus. |
Top Pathways | mRNA surveillance pathway, Influenza A |
Human CPSF30 full length protein - ab140737 from Abcam
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Human CPSF30 full length protein - ab161192 from Abcam
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NAR / CPSF4 Antibody Blocking Peptide - LS-E14897 from LifeSpan Bioscience
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NAR / CPSF4 Antibody Blocking Peptide - LS-E10224 from LifeSpan Bioscience
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CPSF4 Recombinant Protein - H00010898-P01 from Novus Biologicals
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Recombinant Human CPSF4 Protein - NBP2-22783 from Novus Biologicals
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CPSF4-Antibody-Center-Blocking-Peptide - BP9617c from Abgent, a WuXi AppTec company
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Human CPSF4 protein - orb191111 from Biorbyt
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CPSF4 Blocking Peptide - 33R-8599 from Fitzgerald
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CPSF4 protein (His tag) - 80R-2727 from Fitzgerald
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CPSF4 (1-244, His-tag) - AR50847PU-N from Acris Antibodies
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CPSF4 (1-244, His-tag) - AR50847PU-S from Acris Antibodies
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CPSF4 - H00010898-P01 from Acris Antibodies
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CPSF4 - H00010898-P01-10 from Acris Antibodies
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CPSF4 - H00010898-P01-25 from Acris Antibodies
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CPSF4, 1-244aa, Human, His tag, E.coli - 01-P2023 from ARP American Research Products
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CPSF4 fusion protein - ag7103 from Proteintech Group
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CPSF4 fusion protein - ag7232 from Proteintech Group
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Recombinant Human CPSF4, His-tagged - CPSF4-7579H from Creative Biomart
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Recombinant Human Cleavage and polyadenylation specificity factor subunit 4(CPSF - CSB-YP005919HU CSB-EP005919HU CSB-BP005919HU CSB-MP005919HU from Cusabio
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CPSF4, 1-244aa, Human, His tag, E.coli (Denatured) - ATGP2023 from ATGen
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CPSF4 Recombinant Protein Antigen - NBP2-13868PEP from Novus Biologicals
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CPSF4 Peptide, Human - M34GP03592H from Creative Peptides
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CPSF4 - PAT-82022-1 from Nordic BioSite
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CPSF4 - PAT-82022-2 from Nordic BioSite
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