LARP1

Gene Symbol LARP1
Entrez Gene 23367
Alt Symbol LARP
Species Human
Gene Type protein-coding
Description La ribonucleoprotein domain family, member 1
Other Description la-related protein 1
Swissprots Q8N4M2 Q9UFD7 O94836 Q6PKG0 Q8NB73
Accessions EAW61632 EAW61633 EAW61634 Q6PKG0 AB018274 BAA34451 AK091465 BAC03668 AK307554 AK312203 BAG35136 AL133034 CAB61364 BC001460 AAH01460 BC003063 BC010144 BC015573 BC033856 AAH33856 BC038220 BQ003824 BQ422667 EU446783 ABZ92312 JF432319 ADZ15536 XM_005268404 XP_005268461 XM_005268406 XP_005268463 XM_005268407 XP_005268464 XM_005268408 XP_005268465 XM_006714775 XP_006714838 XM_006714776 XP_006714839 XM_011537614 XP_011535916 XM_011537615 XP_011535917 XM_011537616 XP_011535918 XM_011537617 XP_011535919 XM_011537618 XP_011535920 NM_033551 NM_015315 NP_056130
Function RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex. Associates with the mRNA 5'cap in an MTOR-dependent manner and associates with mRNAs containing a 5' terminal oligopyrimidine (5'TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery. Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5'TOP, thereby regulating cell growth and proliferation. {ECO:0000269|PubMed:20430826, ECO:0000269|PubMed:23711370, ECO:0000269|PubMed:24532714}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:20430826, ECO:0000269|PubMed:24532714}.

LARP1 Antibody - 14763 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using LARP1 Antibody.

LARP1 (H-72) - sc-292833 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LARP1 (H-72): sc-292833. Western blot analysis of LARP1 expression in HeLa whole cell lysate.

LARP1 (S-14) - sc-131975 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LARP1 (P-12) - sc-131974 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LARP1 (P-21) - sc-102006 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
LARP1 (P-21): sc-102006. Western blot analysis of LARP1 expression in Hep G2 whole cell lysate.

Anti-LARP1 antibody - ab86359 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human colon carcinoma tissue labelling LARP1 with ab86359 at 1/200 (1µg/ml). Detection: DAB.

Anti-LARP1 antibody - ab101490 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab101490 at 1/250 dilution staining LARP1 in a Formalin-fixed, paraffin-embedded section of Human colon carcinoma by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Detection utilised DAB.

Anti-LARP1 antibody - C-terminal - ab176602 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-LARP1 antibody - C-terminal (ab176602) at 1/500 dilution + Hela cell lysate

Anti-LARP1 / La-Related Protein 1 Antibody (aa107-156) - LS-C107499 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LARP1 / LARP antibody LS-C107499 Western blot of Fetal Stomach lysate.

Anti-LARP1 / La-Related Protein 1 Antibody (aa36-85) - LS-C82434 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
721_B cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 6%.

Anti-LARP1 / La-Related Protein 1 Antibody (N-Terminus) - LS-C116910 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LARP1 / LARP antibody LS-C116910 Western blot of Jurkat lysate.

Anti-LARP1 / La-Related Protein 1 Antibody - LS-C308713 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-LARP1 / La-Related Protein 1 Antibody (aa575-625) - LS-C286772 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human LARP1 by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-LARP used at a dilution of 1:250.

Anti-LARP1 / La-Related Protein 1 Antibody (aa575-625) - LS-C288843 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human LARP1 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-LARP1 used at a dilution of 1:200 (1 Detection: DAB.

Anti-LARP1 / La-Related Protein 1 Antibody (aa275-325) - LS-C288842 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human LARP1 by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-LARP1 used at a dilution of 1:200 (1 Detection: DAB.

LARP1 Antibody - NBP1-19128 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LARP1 Antibody - NBP1-19129 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: LARP1 Antibody [NBP1-19129] - Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells.  Affinity purified rabbit anti-LARP1 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate.  LARP1 was also immunoprecipitated by rabbit anti-LARP1 antibody NBP1-19128, which recognizes an upstream epitope.

LARP1 Antibody - H00023367-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: LARP1 Antibody [H00023367-B01P] - Analysis of LARP1 expression in transfected 293T cell line by LARP1 polyclonal antibody.  Lane 1: LARP1 transfected lysate(112.09 KDa). Lane 2: Non-transfected lysate.

Anti-LARP1, (N-terminal) antibody produced in rabbit - SAB2104703 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-LARP1, antibody produced in rabbit: <B>Cat. No. SAB2104703</B>: Immunoblotting analysis of LARP1 in fetal stomach tissue lysate with LARP1 anitbody at 1 μg/mL.

Anti-LARP1 antibody produced in rabbit - AV41075 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: 721_B (<B>Cat. No. AV41075</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 0.5 μg/mL in cell type 721_B

Anti-LARP1 antibody produced in mouse - SAB1407205 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-LARP1: <B>Cat. No. SAB1407205</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~112.1 kDa using LARP1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-LARP2 antibody produced in rabbit - AV34532 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-LARP2: <B>Cat. No. AV34532</B>: Immunohistochemistry of LARP2 in Human Brain tissue with LARP2 antibody at 4-8 μg/mL.

LARP2 antibody - middle region (ARP34532_T100) - ARP34532_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LARP1 antibody - N-terminal region (ARP41075_P050) - ARP41075_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LARP1 antibody - N-terminal region (ARP41076_P050) - ARP41076_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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