LARP1

Gene Symbol LARP1
Entrez Gene 23367
Alt Symbol LARP
Species Human
Gene Type protein-coding
Description La ribonucleoprotein domain family, member 1
Other Description la-related protein 1
Swissprots Q8N4M2 Q9UFD7 O94836 Q6PKG0 Q8NB73
Accessions EAW61632 EAW61633 EAW61634 Q6PKG0 AB018274 BAA34451 AK091465 BAC03668 AK307554 AK312203 BAG35136 AL133034 CAB61364 BC001460 AAH01460 BC003063 BC010144 BC015573 BC033856 AAH33856 BC038220 BQ003824 BQ422667 EU446783 ABZ92312 JF432319 ADZ15536 XM_005268404 XP_005268461 XM_005268406 XP_005268463 XM_005268407 XP_005268464 XM_005268408 XP_005268465 XM_006714775 XP_006714838 XM_006714776 XP_006714839 XM_011537614 XP_011535916 XM_011537615 XP_011535917 XM_011537616 XP_011535918 XM_011537617 XP_011535919 XM_011537618 XP_011535920 NM_033551 NM_015315 NP_056130
Function RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex. Associates with the mRNA 5'cap in an MTOR-dependent manner and associates with mRNAs containing a 5' terminal oligopyrimidine (5'TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery. Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5'TOP, thereby regulating cell growth and proliferation. {ECO:0000269|PubMed:20430826, ECO:0000269|PubMed:23711370, ECO:0000269|PubMed:24532714}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:20430826, ECO:0000269|PubMed:24532714}.

LARP1 CRISPR/Cas9 KO Plasmid (h) - sc-404097 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LARP1 HDR Plasmid (h) - sc-404097-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LARP1 Double Nickase Plasmid (h) - sc-404097-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LARP1 Double Nickase Plasmid (h2) - sc-404097-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LARP1 CRISPR Activation Plasmid (h) - sc-404097-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LARP1 CRISPR Activation Plasmid (h2) - sc-404097-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LARP1 Lentiviral Activation Particles (h) - sc-404097-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LARP1 Lentiviral Activation Particles (h2) - sc-404097-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LARP1 siRNA (h) - sc-91848 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LARP1 shRNA Plasmid (h) - sc-91848-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LARP1 shRNA (h) Lentiviral Particles - sc-91848-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU077841 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11550 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11550 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

LARP1 siRNA (Human) - CRH8215 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human LARP1 (NM_015315.3) - SHH328499 from Creative biogene

Category siRNA
Species Reactivities Human

LARP1 shRNA Plasmid (Human) - CHH8215 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LARP1 miRNA 3'UTR clone - MiUTR1H-05572 from Creative biogene

Species Reactivities Human
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