Gene Symbol | LARP1 |
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Entrez Gene | 23367 |
Alt Symbol | LARP |
Species | Human |
Gene Type | protein-coding |
Description | La ribonucleoprotein domain family, member 1 |
Other Description | la-related protein 1 |
Swissprots | Q8N4M2 Q9UFD7 O94836 Q6PKG0 Q8NB73 |
Accessions | EAW61632 EAW61633 EAW61634 Q6PKG0 AB018274 BAA34451 AK091465 BAC03668 AK307554 AK312203 BAG35136 AL133034 CAB61364 BC001460 AAH01460 BC003063 BC010144 BC015573 BC033856 AAH33856 BC038220 BQ003824 BQ422667 EU446783 ABZ92312 JF432319 ADZ15536 XM_005268404 XP_005268461 XM_005268406 XP_005268463 XM_005268407 XP_005268464 XM_005268408 XP_005268465 XM_006714775 XP_006714838 XM_006714776 XP_006714839 XM_011537614 XP_011535916 XM_011537615 XP_011535917 XM_011537616 XP_011535918 XM_011537617 XP_011535919 XM_011537618 XP_011535920 NM_033551 NM_015315 NP_056130 |
Function | RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex. Associates with the mRNA 5'cap in an MTOR-dependent manner and associates with mRNAs containing a 5' terminal oligopyrimidine (5'TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery. Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5'TOP, thereby regulating cell growth and proliferation. {ECO:0000269|PubMed:20430826, ECO:0000269|PubMed:23711370, ECO:0000269|PubMed:24532714}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20430826, ECO:0000269|PubMed:24532714}. |
LARP1 / La-Related Protein 1 Antibody Blocking Peptide - LS-E15076 from LifeSpan Bioscience
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LARP1 / La-Related Protein 1 Antibody Blocking Peptide - LS-E15074 from LifeSpan Bioscience
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LARP1 / La-Related Protein 1 Antibody Blocking Peptide - LS-E15075 from LifeSpan Bioscience
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Recombinant Human LARP1 Protein - H00023367-P01 from Novus Biologicals
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LARP1 Blocking Peptide - 33R-3771 from Fitzgerald
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LARP1 Blocking Peptide - 33R-4387 from Fitzgerald
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LARP1 - H00023367-P01 from Acris Antibodies
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LARP1 fusion protein - Ag4645 from Proteintech Group
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Recombinant Human LARP1, His-tagged - LARP1-29045TH from Creative Biomart
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Recombinant Human LARP1, GST-tagged - LARP1-19H from Creative Biomart
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Recombinant Human LARP1, GST-tagged - LARP1-18H from Creative Biomart
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Recombinant Human La-related protein 1(LARP1) ,partial - CSB-YP740795HU CSB-EP740795HU CSB-BP740795HU CSB-MP740795HU from Cusabio
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LARP1 Recombinant Protein Antigen - NBP2-49151PEP from Novus Biologicals
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LARP1 Peptide, Human - M34GP08548H from Creative Peptides
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LARP1 Recombinant Protein Antigen - NBP2-49004PEP from Novus Biologicals
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La-related protein 1 (LARP1), partial, Recombinant Protein - MBS1460224 from MyBioSource
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