ERAP2

Gene Symbol ERAP2
Entrez Gene 64167
Alt Symbol L-RAP, LRAP
Species Human
Gene Type protein-coding
Description endoplasmic reticulum aminopeptidase 2
Other Description leukocyte-derived arginine aminopeptidase
Swissprots Q8TD32 Q6P179 Q9HBX2 Q8WVJ4 Q7Z5K1
Accessions EAW96080 EAW96081 EAW96082 Q6P179 AB109031 BAC78818 AB163917 BAD90015 AF191545 AAG28383 AK074213 AK074281 AK074387 AK312864 BAG35716 AV688559 AY028805 AAK37776 BC017927 AAH17927 BC065240 AAH65240 BU430967 DA990479 DB159802 XM_011543544 XP_011541846 XR_948283 NM_001130140 NP_001123612 NM_022350 NP_071745
Function Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I- binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys. {ECO:0000269|PubMed:12799365, ECO:0000269|PubMed:15908954, ECO:0000269|PubMed:16286653}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:12799365}; Single-pass type II membrane protein {ECO:0000269|PubMed:12799365}.
Tissue Specificity Ubiquitously expressed. Highly expressed in spleen and leukocytes. {ECO:0000269|PubMed:12799365}.

ERAP2 CRISPR/Cas9 KO Plasmid (h) - sc-412989 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERAP2 HDR Plasmid (h) - sc-412989-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERAP2 Double Nickase Plasmid (h) - sc-412989-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERAP2 Double Nickase Plasmid (h2) - sc-412989-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERAP2 CRISPR Activation Plasmid (h) - sc-412989-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERAP2 CRISPR Activation Plasmid (h2) - sc-412989-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERAP2 Lentiviral Activation Particles (h) - sc-412989-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERAP2 Lentiviral Activation Particles (h2) - sc-412989-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERAP2 siRNA (h) - sc-91852 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ERAP2 shRNA Plasmid (h) - sc-91852-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ERAP2 shRNA (h) Lentiviral Particles - sc-91852-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Aminopeptidase LRAP/ERAP2 RNAi - H00064167-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU150601 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7944 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7944 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02818 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02818

ERAP2 siRNA (Human) - CRJ1948 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ERAP2 - MBS8208879 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ERAP2 (NM_022350.3) - SHH286789 from Creative biogene

Category siRNA
Species Reactivities Human

Human ERAP2 siRNA - orb272449 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ERAP2 shRNA Plasmid (Human) - CHJ1948 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ERAP2 miRNA 3'UTR clone - MiUTR4H-TG03137 from Creative biogene

Species Reactivities Human
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