Gene Symbol | DAZ4 |
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Entrez Gene | 57135 |
Alt Symbol | pDP1680, pDP1681 |
Species | Human |
Gene Type | protein-coding |
Description | deleted in azoospermia 4 |
Other Description | deleted in azoospermia protein 4 |
Swissprots | Q86SG3 Q9NR88 Q9NR89 |
Accessions | CBH19254 CBH30638 Q86SG3 AA608617 AF248482 AAF91331 AF248483 AAF91332 AL833003 CAH56318 BC047480 AAH47480 BC047617 AAH47617 XM_005262602 XP_005262659 XM_011531509 XP_011529811 XM_011531510 XP_011529812 NM_001005375 NP_001005375 NM_020420 NP_065153 |
Function | RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11058556}. Nucleus {ECO:0000269|PubMed:11058556}. Note=Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis. |
Tissue Specificity | Testis-specific. Expression restricted to premeiotic germ cells, particularly in spermatogonia (at protein level). {ECO:0000269|PubMed:10936047, ECO:0000269|PubMed:18385127, ECO:0000269|PubMed:19223287}. |
Human Deleted in azoospermia 4 full length protein - ab163497 from Abcam
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DAZ4 Antibody Blocking Peptide - LS-E1762 from LifeSpan Bioscience
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DAZ4 Antibody Blocking Peptide - LS-E14651 from LifeSpan Bioscience
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DAZ4 Antibody Blocking Peptide - LS-E14650 from LifeSpan Bioscience
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Recombinant Human Deleted in azoospermia 4 Protein - H00057135-P01 from Novus Biologicals
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DAZ4-Antibody-Center-Blocking-peptide - BP12556c from Abgent, a WuXi AppTec company
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DAZ4 Blocking Peptide - 33R-6390 from Fitzgerald
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DAZ4 Blocking Peptide - 33R-4176 from Fitzgerald
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DAZ4 - H00057135-P01-10 from Acris Antibodies
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DAZ4 - H00057135-P01-25 from Acris Antibodies
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DAZ4 fusion protein - Ag5116 from Proteintech Group
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Recombinant Human DAZ4, GST-tagged - DAZ4-11835H from Creative Biomart
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Recombinant Human Deleted in azoospermia protein 4(DAZ4) - CSB-YP769764HU CSB-EP769764HU CSB-BP769764HU CSB-MP769764HU from Cusabio
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DAZ4 (transcript variant 2) - TP308193 from Acris Antibodies
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DAZ4 Peptide, Human - M34GP04036H from Creative Peptides
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Deleted in azoospermia protein 4 (DAZ4), Recombinant Protein - MBS1437939 from MyBioSource
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Recombinant Human DAZ4 Protein, GST-tagged - DAZ4-2356H from Creative Biomart
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