Gene Symbol | DAZ4 |
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Entrez Gene | 57135 |
Alt Symbol | pDP1680, pDP1681 |
Species | Human |
Gene Type | protein-coding |
Description | deleted in azoospermia 4 |
Other Description | deleted in azoospermia protein 4 |
Swissprots | Q86SG3 Q9NR88 Q9NR89 |
Accessions | CBH19254 CBH30638 Q86SG3 AA608617 AF248482 AAF91331 AF248483 AAF91332 AL833003 CAH56318 BC047480 AAH47480 BC047617 AAH47617 XM_005262602 XP_005262659 XM_011531509 XP_011529811 XM_011531510 XP_011529812 NM_001005375 NP_001005375 NM_020420 NP_065153 |
Function | RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11058556}. Nucleus {ECO:0000269|PubMed:11058556}. Note=Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis. |
Tissue Specificity | Testis-specific. Expression restricted to premeiotic germ cells, particularly in spermatogonia (at protein level). {ECO:0000269|PubMed:10936047, ECO:0000269|PubMed:18385127, ECO:0000269|PubMed:19223287}. |
DAZ4 (J-23) - sc-133498 from Santa Cruz Biotechnology
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Anti-Deleted in azoospermia 4 antibody - ab197383 from Abcam
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Anti-Deleted in azoospermia 4 antibody - ab94412 from Abcam
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Anti-Deleted in azoospermia 4 antibody - ab112941 from Abcam
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Anti-Deleted in azoospermia 4 antibody - ab69157 from Abcam
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Anti-DAZ4 Antibody (N-Terminus) - LS-C30408 from LifeSpan Bioscience
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Anti-DAZ4 Antibody (aa90-119) - LS-C167273 from LifeSpan Bioscience
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Anti-DAZ4 Antibody (aa90-119, AP) - LS-C234426 from LifeSpan Bioscience
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Anti-DAZ4 Antibody (aa90-119, FITC) - LS-C234429 from LifeSpan Bioscience
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Anti-DAZ4 Antibody (aa90-119, Biotin) - LS-C234428 from LifeSpan Bioscience
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Anti-DAZ4 Antibody (aa90-119, APC) - LS-C234427 from LifeSpan Bioscience
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Anti-DAZ4 Antibody (aa90-119, PE) - LS-C234432 from LifeSpan Bioscience
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Anti-DAZ4 Antibody (aa90-119, Azide-free, HRP) - LS-C249797 from LifeSpan Bioscience
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Anti-DAZ4 Antibody (aa89-120) - LS-C320745 from LifeSpan Bioscience
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Anti-DAZ4 Antibody (aa179-228) - LS-C110499 from LifeSpan Bioscience
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Deleted in azoospermia 4 Antibody - NBP1-57481 from Novus Biologicals
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Deleted in azoospermia 4 Antibody - NBP1-57480 from Novus Biologicals
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Deleted in azoospermia 4 Antibody - H00057135-B01 from Novus Biologicals
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DAZ4 Polyclonal Antibody - bs-13609R from Bioss
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DAZ4 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13609R-A350 from Bioss
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DAZ4 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13609R-A488 from Bioss
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DAZ4 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13609R-A555 from Bioss
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DAZ4 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13609R-A647 from Bioss
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DAZ4 Polyclonal Antibody, Cy3 Conjugated - bs-13609R-Cy3 from Bioss
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DAZ4 Polyclonal Antibody, Cy5 Conjugated - bs-13609R-Cy5 from Bioss
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