DAZ4

Gene Symbol DAZ4
Entrez Gene 57135
Alt Symbol pDP1680, pDP1681
Species Human
Gene Type protein-coding
Description deleted in azoospermia 4
Other Description deleted in azoospermia protein 4
Swissprots Q86SG3 Q9NR88 Q9NR89
Accessions CBH19254 CBH30638 Q86SG3 AA608617 AF248482 AAF91331 AF248483 AAF91332 AL833003 CAH56318 BC047480 AAH47480 BC047617 AAH47617 XM_005262602 XP_005262659 XM_011531509 XP_011529811 XM_011531510 XP_011529812 NM_001005375 NP_001005375 NM_020420 NP_065153
Function RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11058556}. Nucleus {ECO:0000269|PubMed:11058556}. Note=Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.
Tissue Specificity Testis-specific. Expression restricted to premeiotic germ cells, particularly in spermatogonia (at protein level). {ECO:0000269|PubMed:10936047, ECO:0000269|PubMed:18385127, ECO:0000269|PubMed:19223287}.

DAZ4 CRISPR/Cas9 KO Plasmid (h) - sc-417589 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZ4 HDR Plasmid (h) - sc-417589-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZ4 Double Nickase Plasmid (h) - sc-417589-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZ4 Double Nickase Plasmid (h2) - sc-417589-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZ4 CRISPR Activation Plasmid (h) - sc-417589-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZ4 CRISPR Activation Plasmid (h2) - sc-417589-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZ4 Lentiviral Activation Particles (h) - sc-417589-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZ4 Lentiviral Activation Particles (h2) - sc-417589-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MISSION® esiRNA - EHU114581 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

DAZ4 siRNA (Human) - CRJ1348 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DAZ4 - MBS8213648 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DAZ4 (NM_020420.3) - SHH274645 from Creative biogene

Category siRNA
Species Reactivities Human

DAZ4 shRNA Plasmid (Human) - CHJ1348 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DAZ4 miRNA 3'UTR clone - MiUTR3H-13782 from Creative biogene

Species Reactivities Human

DAZ4 miRNA 3'UTR clone - MiUTR3H-13783 from Creative biogene

Species Reactivities Human
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