IL26

Gene Symbol IL26
Entrez Gene 55801
Alt Symbol AK155, IL-26
Species Human
Gene Type protein-coding
Description interleukin 26
Other Description interleukin-26
Swissprots Q9NPH9
Accessions AAR87776 CAB77049 EAW97181 Q9NPH9 AJ251549 CAB76942 BC066270 AAH66270 BC066271 AAH66271 HQ447556 ADQ32042 XM_011538568 XP_011536870 NM_018402 NP_060872
Function May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. {ECO:0000269|PubMed:14764663, ECO:0000269|PubMed:15178681, ECO:0000269|PubMed:18483078}.
Subcellular Location Secreted {ECO:0000269|PubMed:18483078}.
Tissue Specificity Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells. Expressed in colonic T-cells including Th17 inflammatory T-cells; the expression is significantly increased in serum of patients with Crohn's disease (at protein level). {ECO:0000269|PubMed:18483078}.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

IL-26 (T-12) - sc-168179 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
IL-26 (T-12): sc-168179. Western blot analysis of IL-26 expression in HeLa whole cell lysate.

IL-26 (LL07) - sc-80523 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-IL26 antibody - ab102977 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-IL26 antibody (ab102977) at 1/100 dilution + HL60 cell line lysates at 35 µg

Anti-IL26 antibody [EPR6745] - ab133659 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6745
Anti-IL26 antibody [EPR6745] (ab133659) at 1/1000 dilution + recombinant Human IL26 protein with a proprietary tag at 0.01 µgSecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-IL26 Antibody (aa88-115) - LS-C165201 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of IL26 Antibody in HL-60 cell line lysates (35 ug/lane). IL26 (arrow) was detected using the purified antibody.

Anti-IL26 Antibody (aa22-171, clone 11C31, APC) - LS-C130289 from LifeSpan Bioscience

Prices $590.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
Clone 11C31

Anti-IL26 Antibody (aa88-115, AP) - LS-C236583 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IL26 Antibody (aa88-115, Biotin) - LS-C246776 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IL26 Antibody (aa88-115, APC) - LS-C236584 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IL26 Antibody (N-Terminus) - LS-C151820 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
IL26 / IL-26 antibody Western Blot of HeLa.

Anti-IL26 Antibody (aa47-96) - LS-C151821 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
IL26 / IL-26 antibody Western Blot of ACHN.

Anti-IL26 Antibody (aa88-115, PE) - LS-C246780 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IL26 Antibody (Internal, clone EPR6745) - LS-C154606 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6745
Western blot analysis on 10ng of GST tagged-human IL-26 recombinant protein using anti-IL26 antibody.

Anti-IL26 Antibody (aa88-115, FITC) - LS-C246778 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IL26 Antibody (aa94-124) - LS-C322220 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-IL26 Antibody (aa88-115, Azide-free, HRP) - LS-C249267 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

IL-26/AK155 Antibody - AF1375 from Novus Biologicals

Prices $99.00, $365.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal

IL-26/AK155 Antibody (197505) - MAB1375 from Novus Biologicals

Prices $269.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 197505

IL-26/AK155 Antibody (510414) [Unconjugated] - MAB13751 from Novus Biologicals

Prices $99.00, $259.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 510414
Human peripheral blood mononuclear cells were unstimulated (light orange filled histogram) or treated with PMA and Calcium ionomycin, then stained with Mouse Anti-Human IL‑26/AK155 Monoclonal Antibody (Catalog # MAB13751, dark orange filled histogram) or isotype control (Catalog # MAB002, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG F(ab')2 Secondary Antibody (Catalog # F0102B). To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin.

IL-26/AK155 Antibody - NBP1-98521 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: IL26 Antibody [NBP1-98521] - Titration: 1.0 ug/ml Positive Control: ACHN Whole Cell.

IL-26/AK155 Antibody - NBP1-98520 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: IL26 Antibody [NBP1-98520] - Titration: 1.0 ug/ml Positive Control: Hela Whole Cell.

IL-26/AK155 Antibody (MM0399-6D20) - NBP2-11703 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0399-6D20

IL-26/AK155 Antibody [Biotin] - BAF1375 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

IL-26/AK155 Antibody (510414) [Allophycocyanin] - IC13751A from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 510414
Human CD3+ cells treated with PMA and Calcium Ionomycin were stained with Mouse Anti-Human IL-26/AK155 APC-conjugated Monoclonal Antibody (Catalog # IC13751A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules.

IL-26/AK155 Antibody (510414) [PE] - IC13751P from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 510414
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