IL26

Gene Symbol IL26
Entrez Gene 55801
Alt Symbol AK155, IL-26
Species Human
Gene Type protein-coding
Description interleukin 26
Other Description interleukin-26
Swissprots Q9NPH9
Accessions AAR87776 CAB77049 EAW97181 Q9NPH9 AJ251549 CAB76942 BC066270 AAH66270 BC066271 AAH66271 HQ447556 ADQ32042 XM_011538568 XP_011536870 NM_018402 NP_060872
Function May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. {ECO:0000269|PubMed:14764663, ECO:0000269|PubMed:15178681, ECO:0000269|PubMed:18483078}.
Subcellular Location Secreted {ECO:0000269|PubMed:18483078}.
Tissue Specificity Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells. Expressed in colonic T-cells including Th17 inflammatory T-cells; the expression is significantly increased in serum of patients with Crohn's disease (at protein level). {ECO:0000269|PubMed:18483078}.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Human-IL26-cDNA-Clone - DC08538 from Abgent, a WuXi AppTec company

Prices $230.85
Sizes 10 µg
Species Human
Accession BC066270

IL26 - MBS1275011 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC066271

IL26 - MBS1275020 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC066270

Human IL26 cDNA clone(NM_018402.1) - CDFG001820 from Creative Biomart

Species Human
Accession NM_018402.1

Human IL26 ORF Clone(NM_018402.1) - CDCL167142 from Creative Biomart

Species Human
Accession NM_018402.1

Human IL26 ORF Clone(NM_018402.1) - CDCR303688 from Creative Biomart

Species Human
Accession NM_018402.1

Human IL26 ORF Clone(NM_018402.1) - CDCR303689 from Creative Biomart

Species Human
Accession NM_018402.1

Human IL26 ORF Clone(NM_018402.1) - CDCR303690 from Creative Biomart

Species Human
Accession NM_018402.1

Mouse IL26 ORF clone (NM_018402.1) - CDCL120515 from Creative biogene

Species Human

Human IL26 ORF Clone (BC066270) - CDCS414780 from Creative biogene

Species Human
Accession Q9NPH9

Human IL26 ORF Clone (BC066271) - CDCS414781 from Creative biogene

Species Human
Accession Q9NPH9

Human IL26 cDNA Clone(NM_018402.1) - CDFG001820 from Creative biogene

Species Human

Human IL-26 (NP_060872) VersaClone cDNA - RDC1958 from R&D Systems

Prices $199.00
Sizes 10 µg
Species Human
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