IL26

Gene Symbol IL26
Entrez Gene 55801
Alt Symbol AK155, IL-26
Species Human
Gene Type protein-coding
Description interleukin 26
Other Description interleukin-26
Swissprots Q9NPH9
Accessions AAR87776 CAB77049 EAW97181 Q9NPH9 AJ251549 CAB76942 BC066270 AAH66270 BC066271 AAH66271 HQ447556 ADQ32042 XM_011538568 XP_011536870 NM_018402 NP_060872
Function May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. {ECO:0000269|PubMed:14764663, ECO:0000269|PubMed:15178681, ECO:0000269|PubMed:18483078}.
Subcellular Location Secreted {ECO:0000269|PubMed:18483078}.
Tissue Specificity Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells. Expressed in colonic T-cells including Th17 inflammatory T-cells; the expression is significantly increased in serum of patients with Crohn's disease (at protein level). {ECO:0000269|PubMed:18483078}.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

IL-26 CRISPR/Cas9 KO Plasmid (h) - sc-417604 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-26 HDR Plasmid (h) - sc-417604-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-26 Double Nickase Plasmid (h) - sc-417604-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-26 Double Nickase Plasmid (h2) - sc-417604-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-26 CRISPR Activation Plasmid (h) - sc-417604-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-26 CRISPR Activation Plasmid (h2) - sc-417604-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-26 Lentiviral Activation Particles (h) - sc-417604-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-26 Lentiviral Activation Particles (h2) - sc-417604-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-26 siRNA (h) - sc-72398 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-26 shRNA Plasmid (h) - sc-72398-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-26 shRNA (h) Lentiviral Particles - sc-72398-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-26/AK155 RNAi - H00055801-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU057251 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10616 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10616 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

IL26 siRNA (Human) - CRJ0933 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IL26 - MBS8236359 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IL26 (NM_018402.1) - SHH318797 from Creative biogene

Category siRNA
Species Reactivities Human

IL26 shRNA Plasmid (Human) - CHJ0933 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

IL26 miRNA 3'UTR clone - MiUTR1H-04912 from Creative biogene

Species Reactivities Human
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