RDH5

Gene Symbol RDH5
Entrez Gene 5959
Alt Symbol 9cRDH, HSD17B9, RDH1, SDR9C5
Species Human
Gene Type protein-coding
Description retinol dehydrogenase 5 (11-cis/9-cis)
Other Description 11-cis RDH|11-cis RoDH|11-cis retinol dehydrogenase|9-cis retinol dehydrogenase|9-cis-retinol specific dehydrogenase|retinol dehydrogenase 1|retinol dehydrogenase 5 (11-cis and 9-cis)|short chain dehydrogenase/reductase family 9C member 5|short chain dehydrogenase/reductase family 9C, member 5
Swissprots O00179 Q92781 Q8TAI2
Accessions AAC09250 EAW96825 EAW96826 Q92781 AK293313 BAG56833 AK307157 BC028298 AAH28298 BI765016 BP381700 BU617433 BU731044 DQ426887 HQ447382 ADQ31868 U43559 AAC50725 U89717 AAB93668 NM_001199771 NP_001186700 NM_002905 NP_002896
Function Stereospecific 11-cis retinol dehydrogenase, which catalyzes the final step in the biosynthesis of 11-cis retinaldehyde, the universal chromophore of visual pigments. Also able to oxidize 9-cis-retinol and 13-cis-retinol, but not all- trans-retinol. Active in the presence of NAD as cofactor but not in the presence of NADP. {ECO:0000269|PubMed:10588954, ECO:0000269|PubMed:9115228}.
Subcellular Location Membrane {ECO:0000269|PubMed:11675386}; Peripheral membrane protein {ECO:0000269|PubMed:11675386}. Endoplasmic reticulum lumen {ECO:0000269|PubMed:11675386}.
Tissue Specificity Abundant in the retinal pigment epithelium. Expressed at high levels in mammary tissue, kidney and testis, and at lower levels in liver, heart, adrenal gland, lung, pancreas and skeletal muscle. {ECO:0000269|PubMed:9115228}.
Top Pathways Retinol metabolism

RDH5 CRISPR/Cas9 KO Plasmid (h) - sc-404708 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH5 HDR Plasmid (h) - sc-404708-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH5 Double Nickase Plasmid (h) - sc-404708-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH5 Double Nickase Plasmid (h2) - sc-404708-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH5 CRISPR Activation Plasmid (h) - sc-404708-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH5 CRISPR Activation Plasmid (h2) - sc-404708-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH5 Lentiviral Activation Particles (h) - sc-404708-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH5 Lentiviral Activation Particles (h2) - sc-404708-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH5 siRNA (h) - sc-76380 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RDH5 shRNA Plasmid (h) - sc-76380-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RDH5 shRNA (h) Lentiviral Particles - sc-76380-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RDH5 RNAi - H00005959-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU130301 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2130 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2130 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

RDH5 siRNA (Human) - CRH4033 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RDH5 - MBS8201959 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RDH5 (NM_002905.3) - SHH391516 from Creative biogene

Category siRNA
Species Reactivities Human

Human RDH5 siRNA - orb264535 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RDH5 shRNA Plasmid (Human) - CHH4033 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RDH5 miRNA 3'UTR clone - MiUTR4H-TG07421 from Creative biogene

Species Reactivities Human
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