SV2A

Gene Symbol SV2A
Entrez Gene 9900
Alt Symbol SV2
Species Human
Gene Type protein-coding
Description synaptic vesicle glycoprotein 2A
Other Description -
Swissprots Q9BVZ9 O94841 Q8NBJ6 D3DUZ7 Q7Z3L6 Q5QNX8 Q7L0J3
Accessions CAG34345 CAI12572 CAI12573 CCQ43465 EAW53596 EAW53597 EAW53598 Q7L0J3 AB018279 BAA34456 AK075480 BAC11645 AK291718 BAF84407 AK303161 BAG64262 AM393578 CAL38455 BC000776 AAH00776 BC034038 BC045111 AAH45111 BP214143 BX537754 CAD97824 DA334809 DC305069 EU831489 ACE87176 EU831576 ACE86495 NM_001278719 NP_001265648 NM_014849 NP_055664
Function Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity). {ECO:0000250}.
Subcellular Location Cell junction, synapse {ECO:0000250|UniProtKB:Q9JIS5}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q02563}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q02563}. Note=Enriched in chromaffin granules, not present in adrenal microsomes. Associated with both insulin granules and synaptic- like microvesicles in insulin-secreting cells of the pancreas (By similarity). Colocalizes with ATP2B1 at photoreceptor synaptic terminals. {ECO:0000250|UniProtKB:Q02563, ECO:0000250|UniProtKB:Q9JIS5}.
Top Pathways ECM-receptor interaction

SV2A (E-8) - sc-376234 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SV2A (E-8): sc-376234. Western blot analysis of SV2A expression in rat cerebellum tissue extract.

SV2A (R-16) - sc-11939 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SV2A (R-16): sc-11939. Western blot analysis of SV2A expression in mouse brain tissue extract.

SV2A (R-300) - sc-28955 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

SV2A (E-15) - sc-11936 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SV2A (E-15): sc-11936. Western blot analysis of SV2A expression in mouse brain (A), rat cerebellum (B) and rat hypothalamus (C) extracts.

Anti-SV2A antibody - ab32942 from Abcam

Prices $398.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : MarkerLanes 2 - 4 : Anti-SV2A antibody (ab32942) at 1/500 dilutionLane 1 : As aboveLane 2 : Mouse Brain Tissue Lysate at 20 µgLane 3 : Brain (Mouse) Tissue Lysate - normal tissue, 0 days old (ab7188) at 20 µgLane 4 : Rat Brain Tissue Lysate at 20 µgSecondaryLanes 2 - 4 : IR Dye 680 Conjugated Goat anti-Rabbit IgG (H+L) at 1/15000 dilutionPerformed under reducing conditions.

Anti-SV2A antibody - ab77177 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-SV2A antibody (ab77177) at 0.3 µg/ml + rat brain lysate in RIPA buffer at 35 µg

Anti-SV2A antibody - ab101742 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-SV2A antibody [15E11] - ab49572 from Abcam

Prices $391.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 15E11
SV2A was immunoprecipitated using 0.5mg Rat Brain tissue lysate, 5µg of Mouse monoclonal to and 50µl of protein G magnetic beads (+). No antibody was added to the control (-).The antibody was incubated under agitation with Protein G beads for 10min, Rat Brain tissue lysate lysate diluted in RIPA buffer was added to each sample and incubated for a further 10min under agitation.Proteins were eluted by addition of 40µl SDS loading buffer and incubated for 10min at 70°C; 10µl of each sample was separated on a SDS PAGE gel, transferred to a nitrocellulose membrane, blocked with 5% BSA and probed with ab49572.Secondary: Goat polyclonal to mouse IgG light chain specific (HRP) at 1/20,000 dilution.Band: 83kDa; SV2A

Anti-SV2A antibody - C-terminal - ab200153 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-SV2A antibody - C-terminal (ab200153) at 1/1000 dilution + Mouse brain total cell extract

Anti-SV2A / SV Antibody (aa404-670) - LS-C311846 from LifeSpan Bioscience

Prices $250.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SV2A / SV Antibody (aa501-550) - LS-C80993 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Fetal brain cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.

Anti-SV2A / SV Antibody (Internal) - LS-C55543 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.3 ug/ml) staining of rat brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

SV2A Antibody - NBP1-82964 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SV2A Antibody [NBP1-82964] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.

SV2A Antibody - NB100-41402 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

SV2A Antibody - NBP1-59666 from Novus Biologicals

Prices $369.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SV2A Antibody [NBP1-59666] - Human Brain lysate, concentration 0.2-1 ug/ml.

SV2A Antibody - NBP1-46367 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SV2A Antibody - 30910002 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ELISA: SV2A Antibody [30910002]

SV2A Antibody - H00009900-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

SV2A Polyclonal Antibody - bs-2407R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Anti-SV2A Polyclonal Antibody, Unconjugated (bs-2407R) at 1:200 followed by conjugation to the secondary antibody and DAB staining\\n

Anti-SV2A antibody produced in rabbit - AV47093 from Sigma-Aldrich

Prices $347.50, $347.50
Sizes 50 µg, 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: fetal brain (<B>Cat. No. AV47093</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 0.5 μg/mL in cell type fetal brain

Anti-SV2A antibody produced in goat - SAB2501005 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SV2A: <B>Cat. No. SAB2501005</B>: (0.3 μg/mL) staining of rat brain lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SV2A antibody produced in rabbit - HPA007863 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-SV2A: <B>Cat. No. HPA007863</B>: Immunofluorescent staining of human cell line U-251MG shows positivity in cytoplasm.

SV2A antibody - middle region (ARP47093_P050) - ARP47093_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SV2A-Antibody - AF2052a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF2052a (0.3 µg/ml) staining of rat brain lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

SV2A antibody - orb13702 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed paraffin embedded rat brain tissue using SV2A antibody (dilution at 1:200)
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