JCHAIN

Gene Symbol JCHAIN
Entrez Gene 3512
Alt Symbol IGCJ, IGJ, JCH
Species Human
Gene Type protein-coding
Description joining chain of multimeric IgA and IgM
Other Description IgJ chain|J chain|immunoglobulin J chain|immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
Swissprots P01591
Accessions AAA58902 CAE93903 CAE93904 CBU30463 EAX05626 P01591 AK312014 BAG34952 BC038982 AAH38982 BP221304 BP261870 BP418109 BX648421 DQ884395 ABI63362 XM_006714211 XP_006714274 XM_006714212 XP_006714275 XM_011531925 XP_011530227 XM_011531926 XP_011530228 NM_144646 NP_653247
Function Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.
Subcellular Location Secreted.

Ig J chain (B-6) - sc-271967 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ig J chain (B-6): sc-271967. Western blot analysis of Ig J chain expression in rat liver tissue extract.

Ig J chain (F-12) - sc-133177 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ig J chain (F-12): sc-133177. Western blot analysis of Ig J chain expression in non-transfected: sc-117752 (A) and human Ig J chain transfected: sc-115510 (B) 293T whole cell lysates.

Ig J chain (FL-137) - sc-66928 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Ig J chain (FL-137): sc-66928. Western blot analysis of Ig J chain expression in non-transfected: sc-117752 (A) and human Ig J chain transfected: sc-115510 (B) 293T whole cell lysates.

Ig J chain (D-18) - sc-34651 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Ig J chain (D-18): sc-34651. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells and Interstitial cells.

Ig J chain (P-18) - sc-34652 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Ig J chain (P-18): sc-34652. Western blot analysis of Ig J chain expression in mouse spleen (A) and mouse liver (B) tissue extracts.

Ig J chain (S-16) - sc-34654 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Ig J chain (S-16): sc-34654. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells and Interstitial cells.

Anti-IGJ antibody - ab90978 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-IGJ antibody (ab90978) at 1/100 dilution + Mouse spleen lysate at 35 µg

Anti-IGJ antibody - ab70042 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-IGJ antibody (ab70042) at 1/500 dilution + human colon tissue lysate at 25 µgSecondaryHRP-conjugated goat anti-mouse IgG at 1/2500 dilution

Anti-IGJ antibody - ab100899 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Staining of Human IGJ in a Formalin/PFA-fixed paraffin-embedded section of Human Tonsil using ab100899 at a dilution of 1/100.

Anti-IGJ antibody [3H7] - ab119257 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3H7
All lanes : Anti-IGJ antibody [3H7] (ab119257) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY IGJ cDNALysates/proteins at 5 µg per lane.

Anti-IGJ antibody [9C3] - ab136299 from Abcam

Prices $370.00
Sizes 1 mg
Host Mouse
Clonality Monoclonal
Clone 9C3

Anti-IGJ antibody [EPR13794] - ab192604 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13794
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human tonsil tissue labeling IGJ with ab192604 at 1/8000 dilution and HRP Polymer for Rabbit/Mouse IgG. Counterstained with Hematoxylin. Negative control also shown.

Anti-IGJ antibody [KT109] - ab169854 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone KT109
Anti-IGJ antibody [KT109] (ab169854) at 1 µg/ml + Purified serum IgA.

Anti-IGJ antibody, prediluted - ab100900 from Abcam

Prices $370.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
Staining of Human IGJ in a Formalin/PFA-fixed paraffin-embedded section of Human Tonsil using ab100900.

Anti-IGJ antibody [SP105] - ab105229 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone SP105
ab105229, at 1/100 dilution, staining IGJ in formalin-fixed, paraffin-embedded Human tonsil tissue by Immunohistochemistry.

Anti-JCHAIN / Ig J Chain Antibody - LS-C24923 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-JCHAIN / Ig J Chain Antibody (clone Mc19-9) - LS-C58617 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone Mc19-9

Anti-JCHAIN / Ig J Chain Antibody (N-Terminus) - LS-C146040 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
IGJ antibody LS-C146040 Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.

Anti-JCHAIN / Ig J Chain Antibody - LS-C185094 from LifeSpan Bioscience

Prices $575.00
Sizes 1 ml
Host Goat
Clonality Polyclonal

Anti-JCHAIN / Ig J Chain Antibody - LS-C191534 from LifeSpan Bioscience

Prices $415.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal

Anti-JCHAIN / Ig J Chain Antibody (clone 2B9) - LS-C337607 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2B9
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IGJ (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IGJ.

Anti-JCHAIN / Ig J Chain Antibody (C-Terminus) - LS-C210569 from LifeSpan Bioscience

Prices $360.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of Human Tonsil stained with anti-J-chain antibody

Anti-JCHAIN / Ig J Chain Antibody (clone 3H7) IHC-plus™ - LS-B9309 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 3H7
Anti-IGJ antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-JCHAIN / Ig J Chain Antibody (clone 3B3) - LS-C173681 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3B3
IHC of paraffin-embedded Human lymphoma tissue using anti-IGJ mouse monoclonal antibody.

Anti-JCHAIN / Ig J Chain Antibody (aa32-61) - LS-C99276 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded mouse spleen reacted with IGJ Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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