Gene Symbol | JCHAIN |
---|---|
Entrez Gene | 3512 |
Alt Symbol | IGCJ, IGJ, JCH |
Species | Human |
Gene Type | protein-coding |
Description | joining chain of multimeric IgA and IgM |
Other Description | IgJ chain|J chain|immunoglobulin J chain|immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides |
Swissprots | P01591 |
Accessions | AAA58902 CAE93903 CAE93904 CBU30463 EAX05626 P01591 AK312014 BAG34952 BC038982 AAH38982 BP221304 BP261870 BP418109 BX648421 DQ884395 ABI63362 XM_006714211 XP_006714274 XM_006714212 XP_006714275 XM_011531925 XP_011530227 XM_011531926 XP_011530228 NM_144646 NP_653247 |
Function | Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component. |
Subcellular Location | Secreted. |