EPHB6

Gene Symbol	EPHB6
Entrez Gene	2051
Alt Symbol	HEP
Species	Human
Gene Type	protein-coding
Description	EPH receptor B6
Other Description	ephrin type-B receptor 6|human kinase-defective Eph-family receptor protein|tyrosine-protein kinase-defective receptor EPH-6
Swissprots	A4D2I7 O15197 Q2TB24 D3DXD3 A8CDT5 Q2TB23
Accessions	AAD03058 AAP20939 EAL23775 EAW51900 EAW51901 EAW51902 EAW51903 O15197 AL832533 BC015495 BC047892 BC051028 BC056159 BC110606 AAI10607 BC110607 AAI10608 BM665491 BX410199 BX414750 CN283348 D83492 BAA21560 EU054308 ABV55388 HY096414 XM_006715881 XP_006715944 XM_011515879 XP_011514181 XM_011515880 XP_011514182 XM_011515881 XP_011514183 XM_011515882 XP_011514184 XM_011546506 XP_011544808 XM_011546507 XP_011544809 XM_011546508 XP_011544810 XM_011546509 XP_011544811 XM_011546510 XP_011544812 XM_011546511 XP_011544813 NM_001280794 NP_001267723 NM_001280795 NP_001267724 NM_004445 NP_004436 NR_104001
Function	Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2. {ECO:0000269|PubMed:12517763, ECO:0000269|PubMed:15955811}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed in brain. Expressed in non invasive breast carcinoma cell lines (at protein level). Strong expression in brain and pancreas, and weak expression in other tissues, such as heart, placenta, lung, liver, skeletal muscle and kidney. Expressed in breast non invasive tumors but not in metastatic lesions. Isoform 3 is expressed in cell lines of glioblastomas, anaplastic astrocytomas, gliosarcomas and astrocytomas. Isoform 3 is not detected in normal tissues. {ECO:0000269|PubMed:18754880, ECO:0000269|PubMed:19234485, ECO:0000269|PubMed:9207182}.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat EPHB6 / EPH Receptor B6 ELISA Kit (Cell-Based ELISA) - LS-F1970 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate

Phosphotyrosine EPHB6 / Ephrin Type-B Receptor 6 ELISA Kit - RAB0954 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

Custom Human EphB6 ELISA - ELH-EPHB6 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

EPH receptor B6, ELISA Kit - MBS932048 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human EPHB6 is typically less than 19.5 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 78 pg/ml -5000 pg/ml.

EPHB6 Colorimetric Cell-Based ELISA Kit - CB5242 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Human EphB6 ELISA Pair Set - SEK10197-5 from Sino Biological Category ELISA Kit Prices $350.00, $350.00 Sizes 5 plates, 15 plates

Human Ephrin type-B receptor 6(EPHB6) ELISA kit - CSB-EL007733HU from Cusabio Category ELISA Kit Sensitivity 19.5 pg/ml. Range 78 pg/ml-5000 pg/ml

Human EphB6 ELISA Kit - NS-E10191 from Novatein Biosciences Category ELISA Kit Prices $459.00 Sizes 96 t Sensitivity 5 pg/mL Range 9.4 - 600 pg/ml

EPHB6 ELISA Kit - DEIA-XYA606 from Creative Diagnostics Category ELISA Kit

Human EphB6 ELISA - RAB1442 from Sigma-Aldrich Prices $615.00 Sizes 1 kt

Human Ephrin type-B receptor 6 (EPHB6) ELISA Kit - EKC33590 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 19.5 pg/ml Range 78 pg/ml-5000 pg/ml

Custom Human EphB6 ELISA - ELH-EPHB6-1 from RayBiotech Category ELISA Kit Prices $627.00, $1,128.60, $2,508.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Custom Human Phosphotyrosine EphB6 ELISA - PEL-EPHB6-Y-1 from RayBiotech Category ELISA Kit Prices $627.00, $1,128.60, $2,508.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human EPHB6 ELISA Kit - E013304 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human EPHB6 is typically less than 19.5 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the me

EPHB6 ELISA Kit (Human) (OKCA01227) - OKCA01227 from Aviva Systems Biology Category ELISA Kit Prices $600.00 Sizes 96 wells Sensitivity 19.5 pg/mL Range 78 - 5,000 pg/mL

EPHB6 Colorimetric Cell-Based ELISA Kit - EKA50205 from Biomatik Category ELISA Kit Prices $399.00 Sizes 96 tests Sensitivity At least 5000 cells/well Range Qualitative

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