TPBG

Gene Symbol	TPBG
Entrez Gene	7162
Alt Symbol	5T4, 5T4AG, M6P1, WAIF1
Species	Human
Gene Type	protein-coding
Description	trophoblast glycoprotein
Other Description	5T4 oncofetal antigen\|5T4 oncofetal trophoblast glycoprotein\|5T4 oncotrophoblast glycoprotein\|wnt-activated inhibitory factor 1
Swissprots	A8K555 Q13641
Accessions	CAA09930 CAF06467 CAF85961 EAW48683 Q13641 AI342491 AI857997 AK074786 AK074790 BAG52001 AK291170 BAF83859 BC037161 AAH37161 Z29083 CAA82324 XM_011536097 XP_011534399 NM_001166392 NP_001159864 NM_006670 NP_006661
Function	May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a- dependent LRP6 internalization. {ECO:0000269\|PubMed:22100263}.
Subcellular Location	Cell membrane {ECO:0000269\|PubMed:24582434}; Single-pass type I membrane protein {ECO:0000269\|PubMed:24582434}.
Tissue Specificity	Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.

TPBG (P-14) - sc-162342 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-5T4 antibody - ab88091 from Abcam

Prices	$385.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-5T4 antibody (ab88091) at 5 µg/ml + HeLa cell lysate at 50 µg

Anti-5T4 antibody - ab130522 from Abcam

Prices	$359.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-5T4 antibody (ab130522) at 1/100 dilution + A2058 cell line lysate at 35 µg

Anti-5T4 antibody [EPR5530] - ab129058 from Abcam

Prices	$379.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR5530

Anti-5T4 antibody [EPR5530] (ab129058) at 1/5000 dilution (purified) + Rat brain at 20 µgSecondaryHRP goat-anti rabbit (H+L) at 1/1000 dilution

Anti-5T4 antibody - N-terminal - ab170983 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-5T4 antibody - N-terminal (ab170983) at 1 µg/ml + Mouse heart lysate at 10 µg

Anti-TPBG / 5T4 Antibody (aa169-197, APC) - LS-C272000 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-TPBG / 5T4 Antibody (aa169-197, Biotin) - LS-C272001 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-TPBG / 5T4 Antibody (aa169-197, FITC) - LS-C272003 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-TPBG / 5T4 Antibody (aa169-197, Azide-free, HRP) - LS-C272004 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-TPBG / 5T4 Antibody (aa169-197, PE) - LS-C272006 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-TPBG / 5T4 Antibody (aa168-197) - LS-C325883 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-TPBG / 5T4 Antibody (Extracellular Domain, clone EPR5529) - LS-C138863 from LifeSpan Bioscience

Prices	$485.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR5529

Western blot analysis on (A) HT-29, (B) HT-1376, and (C) Caco-2 cell lysates using anti-TPBG antibody.

Anti-TPBG / 5T4 Antibody (clone 3D6) - LS-C198359 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	3D6

Detection limit for recombinant GST tagged TPBG is approximately 0.1 ng/ml as a capture antibody.

Anti-TPBG / 5T4 Antibody (N-Terminus) - LS-C170150 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-TPBG / 5T4 Antibody (aa169-197) - LS-C160133 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

TPBG Antibody western blot of A2058 cell line lysates (35 ug/lane). The TPBG antibody detected the TPBG protein (arrow).

Anti-TPBG / 5T4 Antibody (aa32-351) - LS-C314511 from LifeSpan Bioscience

Prices	$375.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-TPBG / 5T4 Antibody (aa34-356) - LS-C314512 from LifeSpan Bioscience

Prices	$385.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-TPBG / 5T4 Antibody (Intracellular Domain, clone EPR5530) IHC-plus™ - LS-B9446 from LifeSpan Bioscience

Prices	$395.00
Sizes	50 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR5530

Anti-TPBG / 5T4 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-TPBG / 5T4 Antibody (aa31-355) - LS-C124311 from LifeSpan Bioscience

Prices	$605.00
Sizes	100 µg
Host	Sheep
Clonality	Polyclonal

Anti-TPBG / 5T4 Antibody (aa31-355, Biotin) - LS-C126086 from LifeSpan Bioscience

Prices	$650.00
Sizes	50 µg
Host	Sheep
Clonality	Polyclonal

Anti-TPBG / 5T4 Antibody (aa31-355) - LS-C126087 from LifeSpan Bioscience

Prices	$465.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-TPBG / 5T4 Antibody (aa169-197, AP) - LS-C271999 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

5T4 Antibody (524731) - MAB4975 from Novus Biologicals

Prices	$249.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	524731

Immunohistochemistry 5T4 Antibody (524731)

5T4 Antibody - AF4975 from Novus Biologicals

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Sheep
Clonality	Polyclonal

5T4 Antibody - NBP1-90315 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: 5T4 Antibody [NBP1-90315] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

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