TPBG

Gene Symbol TPBG
Entrez Gene 7162
Alt Symbol 5T4, 5T4AG, M6P1, WAIF1
Species Human
Gene Type protein-coding
Description trophoblast glycoprotein
Other Description 5T4 oncofetal antigen|5T4 oncofetal trophoblast glycoprotein|5T4 oncotrophoblast glycoprotein|wnt-activated inhibitory factor 1
Swissprots A8K555 Q13641
Accessions CAA09930 CAF06467 CAF85961 EAW48683 Q13641 AI342491 AI857997 AK074786 AK074790 BAG52001 AK291170 BAF83859 BC037161 AAH37161 Z29083 CAA82324 XM_011536097 XP_011534399 NM_001166392 NP_001159864 NM_006670 NP_006661
Function May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a- dependent LRP6 internalization. {ECO:0000269|PubMed:22100263}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:24582434}; Single-pass type I membrane protein {ECO:0000269|PubMed:24582434}.
Tissue Specificity Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.

TPBG CRISPR/Cas9 KO Plasmid (h) - sc-411041 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPBG HDR Plasmid (h) - sc-411041-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPBG Double Nickase Plasmid (h) - sc-411041-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPBG Double Nickase Plasmid (h2) - sc-411041-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPBG CRISPR Activation Plasmid (h) - sc-411041-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPBG CRISPR Activation Plasmid (h2) - sc-411041-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPBG Lentiviral Activation Particles (h) - sc-411041-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPBG Lentiviral Activation Particles (h2) - sc-411041-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPBG siRNA (h) - sc-95431 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TPBG shRNA Plasmid (h) - sc-95431-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TPBG shRNA (h) Lentiviral Particles - sc-95431-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

5T4 RNAi - H00007162-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU053631 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21856 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21856 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06191 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06191

TPBG siRNA (Human) - CRH4913 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TPBG - MBS8209733 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TPBG (NM_006670.4) - SHH433160 from Creative biogene

Category siRNA
Species Reactivities Human

Human TPBG siRNA - orb265415 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TPBG shRNA Plasmid (Human) - CHH4913 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TPBG miRNA 3'UTR clone - MiUTR3H-02290 from Creative biogene

Species Reactivities Human
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