Gene Symbol | TPBG |
---|---|
Entrez Gene | 7162 |
Alt Symbol | 5T4, 5T4AG, M6P1, WAIF1 |
Species | Human |
Gene Type | protein-coding |
Description | trophoblast glycoprotein |
Other Description | 5T4 oncofetal antigen|5T4 oncofetal trophoblast glycoprotein|5T4 oncotrophoblast glycoprotein|wnt-activated inhibitory factor 1 |
Swissprots | A8K555 Q13641 |
Accessions | CAA09930 CAF06467 CAF85961 EAW48683 Q13641 AI342491 AI857997 AK074786 AK074790 BAG52001 AK291170 BAF83859 BC037161 AAH37161 Z29083 CAA82324 XM_011536097 XP_011534399 NM_001166392 NP_001159864 NM_006670 NP_006661 |
Function | May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a- dependent LRP6 internalization. {ECO:0000269|PubMed:22100263}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:24582434}; Single-pass type I membrane protein {ECO:0000269|PubMed:24582434}. |
Tissue Specificity | Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma. |
Human 5T4 full length protein - ab159737 from Abcam
|
||||||||||
Human 5T4 protein fragment - ab159738 from Abcam
|
||||||||||
TPBG / 5T4 Antibody Blocking Peptide - LS-E4744 from LifeSpan Bioscience
|
||||||||||
TPBG / 5T4 Antibody Blocking Peptide - LS-E13326 from LifeSpan Bioscience
|
||||||||||
Recombinant Human 5T4 Protein - H00007162-P01 from Novus Biologicals
|
||||||||||
Recombinant Human 5T4 Protein - H00007162-Q01 from Novus Biologicals
|
||||||||||
TPBG-Antibody-Center-Blocking-Peptide - BP17116c from Abgent, a WuXi AppTec company
|
||||||||||
Trophoblast glycoprotein (TPBG) - H00007162-P01-10 from Acris Antibodies
|
||||||||||
Trophoblast glycoprotein (TPBG) - H00007162-P01-25 from Acris Antibodies
|
||||||||||
Trophoblast glycoprotein (TPBG) - H00007162-Q01-10 from Acris Antibodies
|
||||||||||
Trophoblast glycoprotein (TPBG) - H00007162-Q01-25 from Acris Antibodies
|
||||||||||
Recombinant Trophoblast Glycoprotein (TPBG) - RPA434Hu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Trophoblast Glycoprotein (TPBG) - RPA434Mu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Trophoblast Glycoprotein (TPBG) - RPA434Hu01 from Cloud-clone
|
||||||||||
Recombinant Human Trophoblast glycoprotein(TPBG) - CSB-YP024093HU CSB-EP024093HU CSB-BP024093HU CSB-MP024093HU from Cusabio
|
||||||||||
Trophoblast Glycoprotein Protein (Recombinant) - abx167128 from Abbexa
|
||||||||||
Trophoblast glycoprotein (TPBG) - TP303484 from Acris Antibodies
|
||||||||||
Recombinant Human TPBG protein, MYC/DDK-tagged - TPBG-190H from Creative Biomart
|
||||||||||
5T4 Recombinant Protein Antigen - NBP1-90315PEP from Novus Biologicals
|
||||||||||
TPBG Peptide, Human - M34GP16468H from Creative Peptides
|
||||||||||
Trophoblast glycoprotein (17-25) - ta-412 from Creative Peptides
|
||||||||||
Recombinant Trophoblast Glycoprotein (TPBG) - RPU53907 from Biomatik
|
||||||||||
TPBG Recombinant Protein (OPCD07660) - OPCD07660 from Aviva Systems Biology
|
||||||||||
Recombinant Human TPBG Protein, His-Avi-tagged, Biotinylated - TPBG-33H from Creative Biomart
|
||||||||||
Recombinant Human TPBG protein, His/Avi-tagged - TPBG-375H from Creative Biomart
|